TY - JOUR T1 - Heat Development During Medical Drilling: Influencing Factors and Examination Methods – Overview and First Results JF - In Vivo JO - In Vivo SP - 3011 LP - 3017 DO - 10.21873/invivo.12596 VL - 35 IS - 6 AU - OLE JUNG AU - CAROLIN LINDNER AU - SVEN PANTERMEHL AU - MIKE BARBECK Y1 - 2021/11/01 UR - http://iv.iiarjournals.org/content/35/6/3011.abstract N2 - In many medical disciplines, the process of drilling into the bone plays a crucial role for the implantation or fixation of implants or reconstruction plates. During the bone drilling process, heat is generated on the drill head and within the surrounding tissue. As a result, the increased temperature can lead to thermal damage and related necrosis of the (bone) tissue. This tissue damage is dependent on different drilling parameters and can have important influence on the following tissue healing cascade and finally on implant surveillance. In this context, the present short review elucidates the current state of scientific knowledge with regard to the heat-triggering factors during the bony drilling process and how these factors can be better understood and prevented, now and in the future, through new research approaches. External and internal influencing factors during the drilling process are distinguished and methods to examine the temperature changes are compared. This mini-review further demonstrates first preliminary results of the inflammatory tissue reactions to inadequate drilling processes. Furthermore, possible solutions of new standardized ex vivo-measurement methods to better understand the factors influencing the development of heat and to reduce animal experiments are herein discussed. ER -