RT Journal Article SR Electronic T1 Drug Repositioning With an Anticancer Effect: Contributions to Reduced Cancer Incidence in Susceptible Individuals JF In Vivo JO In Vivo FD International Institute of Anticancer Research SP 3039 OP 3044 DO 10.21873/invivo.12599 VO 35 IS 6 A1 SUNGPIL YOON A1 HYUNG SIK KIM YR 2021 UL http://iv.iiarjournals.org/content/35/6/3039.abstract AB Certain diseases and age groups are associated with a higher incidence of cancer. Cancer prevention can be achieved using repositioned drugs that have anticancer ability, thereby reducing the incidence of cancer in susceptible individuals. This implies that the selection of repositioned drugs can have dual benefits: controlling pre-existing diseases and facilitating cancer prevention. This report outlines the rationale underlying drug repositioning for medications with an anticancer effect and discusses its advantages. We discuss repositioned drugs with anticancer effects that may contribute to cancer prevention in susceptible individuals and the general population with temporary, treatable conditions. The discussion of drug repositioning in this review should facilitate the initiation of clinical trials and lead to therapeutic application of such drugs to reduce the incidence of cancer in susceptible individuals.