PT  - JOURNAL ARTICLE
AU  - LILIANA BELGIOIA
AU  - ALESSANDRA FOZZA
AU  - LUCA TRAPANI
AU  - LUCA CARMISCIANO
AU  - FRANCESCA CAVAGNETTO
AU  - STEFANO AGOSTINELLI
AU  - MARINA GUENZI
AU  - DANIELE FRIEDMAN
AU  - PIERO FREGATTI
AU  - RENZO CORVÒ
TI  - Ten Daily Fractions for Whole Breast Cancer Irradiation: Long Term Results
AID  - 10.21873/invivo.12576
DP  - 2021 Sep 01
TA  - In Vivo
PG  - 2875--2880
VI  - 35
IP  - 5
4099  - http://iv.iiarjournals.org/content/35/5/2875.short
4100  - http://iv.iiarjournals.org/content/35/5/2875.full
SO  - In Vivo2021 Sep 01; 35
AB  - Background/Aim: To report the feasibility and oncological outcomes in breast cancer patients treated with a short hypofractionated radiotherapy schedule. Patients and Methods: We evaluated 380 breast cancer patients treated with ten daily fractions of radiotherapy up to 39 Gy on tumor bed. Primary endpoint was local relapse rate (LRR). Secondary endpoints were overall survival (OS) and metastasis-free survival (MFS). Results: The median follow up was 5.0 years. Two- and 5-year LRR rates were 0.2 and 2%, respectively. Two- and 5-year MFS rates were 96.1% and 90.5%, respectively. Two and 5-year OS rates were 97.4% and 95%, respectively. Conclusion: This short schedule may represent an alternative option to standard mild hypofractionated radiotherapy in breast cancer patients due to its excellent feasibility and very low recurrence rate.