RT Journal Article SR Electronic T1 Extremely Advanced Breast Cancer Presentation: Possible Effect of Coronavirus Pandemic Anxiety JF In Vivo JO In Vivo FD International Institute of Anticancer Research SP 2331 OP 2335 DO 10.21873/invivo.12508 VO 35 IS 4 A1 GIANLUCA VANNI A1 FRANCESCA SANTORI A1 MARCO PELLICCIARO A1 MARCO MATERAZZO A1 JONATHAN CASPI A1 ALESSANDRA VITTORIA GRANAI A1 ADRIANO DE MAJO A1 FRANCESCA SERVADEI A1 ERICA GIACOBBI A1 TOMMASO PERRETTA A1 ROSARIA MEUCCI A1 CHIARA ADRIANA PISTOLESE A1 ORESTE CLAUDIO BUONOMO YR 2021 UL http://iv.iiarjournals.org/content/35/4/2331.abstract AB Background/Aim: Corona virus infection dramatically spread worldwide during 2020 and extraordinary restrictions have been implemented in order to reduce viral transmission. These measures compelled a complete restructuring of the health system, including temporary cancer screening suspension and a significant slow-down in cancer diagnoses and treatments. Case Report: We report five cases of extremely advanced breast cancer referred to our Department amid the COVID-19 pandemic. These patients exhibited a poor prognosis or worse quality of life due to their oncological disease. Conclusion: In our opinion, both the slow-down of diagnosis and treatment of oncological disease and anxiety over COVID-19 influenced this presentation. Moreover, other patients were unable to receive palliative care. Hopefully, these cases will not develop into extremely advanced-stage disease, and we will be able to provide at least the necessary palliative care.