TY - JOUR T1 - Identification of an Optimal Population for Allogeneic Hematopoietic Stem Cell Transplantation in Patients With Mature T and NK Cell Neoplasms JF - In Vivo JO - In Vivo SP - 2379 LP - 2390 DO - 10.21873/invivo.12515 VL - 35 IS - 4 AU - EUN HEE JUNG AU - DONG-YEOP SHIN AU - JUNSHIK HONG AU - INHO KIM AU - SUNG-SOO YOON AU - YOUNGIL KOH AU - JA MIN BYUN Y1 - 2021/07/01 UR - http://iv.iiarjournals.org/content/35/4/2379.abstract N2 - Background/Aim: The prognosis of mature T and natural killer (NK) cell neoplasms still remains dismal, despite the advancements in the understanding of the heterogeneous features of these diseases. As allogeneic stem cell transplantation (alloSCT) is an attractive salvage option for relapsed/refractory patients, we conducted this study to identify those who might benefit the most from alloSCT. Patients and Methods: This was a retrospective, single-center, longitudinal cohort study of patients who received alloSCT between December 2019 and January 2000. Results: The median relapse-free survival and overall survival were 4.4 and 10.0 months, respectively. Disease control status at alloSCT and number of previous treatments were associated with survival outcomes. The conditioning intensity did not significantly alter survival. Conclusion: AlloSCT offers a cure chance for selected relapsed or refractory T and NK cell neoplasms, especially when used early and the disease is well controlled prior to transplantation. ER -