RT Journal Article
SR Electronic
T1 Role of the Prognostic Nutritional Index in Patients With Soft-tissue Sarcoma
JF In Vivo
JO In Vivo
FD International Institute of Anticancer Research
SP 2349
OP 2355
DO 10.21873/invivo.12511
VO 35
IS 4
A1 YUMI MATSUYAMA
A1 TOMOKI NAKAMURA
A1 KEISUKE YOSHIDA
A1 KOICHI NAKAMURA
A1 TOMOHITO HAGI
A1 KUNIHIRO ASANUMA
A1 AKIHIRO SUDO
YR 2021
UL http://iv.iiarjournals.org/content/35/4/2349.abstract
AB Background: This study aimed to determine whether the prognostic nutritional index (PNI) can predict the prognosis in patients with soft-tissue sarcoma (STS) before treatment and to examine whether there is an association between PNI values and clinical characteristics. Patients and Methods: The data on 100 patients with primary STS were retrospectively reviewed. The cohort included 55 men and 45 women, with a mean age of 64 years. The mean follow-up duration was 41.7 months. Results: The median PNI was 51.35. The PNI was significantly inversely associated with tumor size, tumor grade, and age. We found that the PNI was a significant prognostic marker for disease-specific and event-free survival using univariate and multivariate analyses. Patients with a low PNI had poorer disease-specific and event-free survival than those with a high PNI. Conclusion: These results suggest that the PNI can be used as a prognostic marker in patients with STS.