TY - JOUR T1 - Quality of Life in Early Breast Cancer Patients: A Prospective Observational Study Using the FACT-B Questionnaire JF - In Vivo JO - In Vivo SP - 1821 LP - 1828 DO - 10.21873/invivo.12443 VL - 35 IS - 3 AU - LUCIA ANNA URSINI AU - MARIANNA NUZZO AU - CONSUELO ROSA AU - FIORELLA CRISTINA DI GUGLIELMO AU - MONICA DI TOMMASO AU - MARIANNA TRIGNANI AU - MARZIA BORGIA AU - ALBINA ALLAJBEJ AU - FABIOLA PATANI AU - CLELIA DI CARLO AU - ANNAMARIA PORRECA AU - MARTA DI NICOLA AU - DOMENICO GENOVESI AU - LUCIANA CARAVATTA Y1 - 2021/05/01 UR - http://iv.iiarjournals.org/content/35/3/1821.abstract N2 - Background/Aim: Quality of life (QoL) in early breast cancer (BC) treatment may be affected by acute and late toxicities. This study evaluated the impact of radiotherapy (RT) schedules, treatment-related toxicities, hormone therapy (HT) and age on QoL. Patients and Methods: Ninety-five patients answered the FACT-B 4.0 questionnaire. Acute or late toxicities were recorded at each follow-up visit. Results: The median trend of the QoL subscales was stable during all questionnaires. HT negatively impacted on Functional Assessment of Cancer Therapy-General-Total, functional and emotional wellbeing. No difference was recorded between RT schedules and toxicity. No significant differences for age were detected in QoL. Conclusion: RT seems not to influence QoL of BC patients, in terms of fractionation regimen or RT-related side-effects. Moreover, women having systemic HT experienced a QoL worse than patients treated with RT only. Further and long-term protocols are needed to improve the validity of the tool. ER -