RT Journal Article
SR Electronic
T1 Impact of Colon Cancer Location on the Prognostic Significance of Nutritional Indexes and Inflammatory Markers
JF In Vivo
JO In Vivo
FD International Institute of Anticancer Research
SP 1261
OP 1269
DO 10.21873/invivo.12377
VO 35
IS 2
A1 TAMURO HAYAMA
A1 TSUYOSHI OZAWA
A1 KENTARO ASAKO
A1 RIE KONDO
A1 KOHEI ONO
A1 YUKA OKADA
A1 MITSUO TSUKAMOTO
A1 YOSHIHISA FUKUSHIMA
A1 RYU SHIMADA
A1 KEIJIRO NOZAWA
A1 KEIJI MATSUDA
A1 SHOICHI FUJII
A1 TAKEO FUKAGAWA
A1 YOJIRO HASHIGUCHI
YR 2021
UL http://iv.iiarjournals.org/content/35/2/1261.abstract
AB Background/Aim: The prognosis of colorectal cancer is reported to differ depending on the tumor site, and clinical differences depending on the site of occurrence have gained attention. The aim was to compare nutrition index and inflammatory markers according to the site of colon cancer. Patients and Methods: We retrospectively analyzed 272 cases of stage I-III colon cancer (55% males, 45% females). The clinical characteristics, nutrition index and inflammatory markers were compared between patients with right colon cancer (RCC, n=119) and those with left colon cancer (LCC, n=153), and the relapse-free survival was then compared. Results: RCC was associated with older age (p=0.03), female gender (p=0.003), higher T stage (p=0.01), elevated platelet/lymphocyte ratio (PLR) (p=0.009), and elevated CONUT score (p=0.028). The prognostic values differed between RCC and LCC (RCC: CONUT score, p=0.04, LCC: PLR, p=0.02). Conclusion: RCC was associated with an elevated CONUT score and PLR. In RCC, the CONUT score was an independent recurrence factor, and in LCC, the PLR was an independent recurrence factor.