TY - JOUR T1 - Prognostic Evaluation of the Site of Invasion in Pathological Stage T3a Renal Cell Carcinoma JF - In Vivo JO - In Vivo SP - 1083 LP - 1089 DO - 10.21873/invivo.12353 VL - 35 IS - 2 AU - GU-SHUN LAI AU - JIAN-RI LI AU - SHIAN-SHIANG WANG AU - CHUAN-SHU CHEN AU - CHUN-KUANG YANG AU - SHENG-CHUN HUNG AU - CHEN-LI CHENG AU - YEN-CHUAN OU AU - KUN-YUAN CHIU Y1 - 2021/03/01 UR - http://iv.iiarjournals.org/content/35/2/1083.abstract N2 - Background/Aim: To investigate the prognostic values of fat invasion (FI) and renal vein invasion (RVI) in pT3a renal cell carcinoma (RCC), as single factors or concomitant presence. Patients and Methods: We retrospectively reviewed the data of 173 patients who underwent radical or partial nephrectomy for RCC in our Institution. Results: At a median follow-up time of 48 months, patients with RVI showed significantly increased risk of disease recurrence and worse cancer-specific survival (CSS) when compared to those with FI (p=0.007, p=0.022, respectively). Having combined RVI and FI did not show inferior prognosis compared to those with RVI only. In multivariable analysis, RVI was an independent factor for disease recurrence (HR=2.06, 95% CI=1.10-3.87, p=0.024) and CSS (HR=2.46, 95% CI=1.01-6.0, p=0.048). Conclusion: For patients with T3a renal tumors, RVI was associated with inferior prognosis compared to those with FI. ER -