RT Journal Article
SR Electronic
T1 Prognostic Evaluation of the Site of Invasion in Pathological Stage T3a Renal Cell Carcinoma
JF In Vivo
JO In Vivo
FD International Institute of Anticancer Research
SP 1083
OP 1089
DO 10.21873/invivo.12353
VO 35
IS 2
A1 GU-SHUN LAI
A1 JIAN-RI LI
A1 SHIAN-SHIANG WANG
A1 CHUAN-SHU CHEN
A1 CHUN-KUANG YANG
A1 SHENG-CHUN HUNG
A1 CHEN-LI CHENG
A1 YEN-CHUAN OU
A1 KUN-YUAN CHIU
YR 2021
UL http://iv.iiarjournals.org/content/35/2/1083.abstract
AB Background/Aim: To investigate the prognostic values of fat invasion (FI) and renal vein invasion (RVI) in pT3a renal cell carcinoma (RCC), as single factors or concomitant presence. Patients and Methods: We retrospectively reviewed the data of 173 patients who underwent radical or partial nephrectomy for RCC in our Institution. Results: At a median follow-up time of 48 months, patients with RVI showed significantly increased risk of disease recurrence and worse cancer-specific survival (CSS) when compared to those with FI (p=0.007, p=0.022, respectively). Having combined RVI and FI did not show inferior prognosis compared to those with RVI only. In multivariable analysis, RVI was an independent factor for disease recurrence (HR=2.06, 95% CI=1.10-3.87, p=0.024) and CSS (HR=2.46, 95% CI=1.01-6.0, p=0.048). Conclusion: For patients with T3a renal tumors, RVI was associated with inferior prognosis compared to those with FI.