RT Journal Article
SR Electronic
T1 Daily Triglyceride Output Volume as an Early Predictor for Chyle Leak Following Pancreaticoduodenectomy
JF In Vivo
JO In Vivo
FD International Institute of Anticancer Research
SP 1271
OP 1276
DO 10.21873/invivo.12378
VO 35
IS 2
A1 TARO SAKAMOTO
A1 NORIMITSU OKUI
A1 FUMITAKE SUZUKI
A1 RYOGA HAMURA
A1 YOSHIHIRO SHIRAI
A1 KOICHIRO HARUKI
A1 KENEI FURUKAWA
A1 TORU IKEGAMI
YR 2021
UL http://iv.iiarjournals.org/content/35/2/1271.abstract
AB Background/Aim: Useful prophylaxes of chyle leak (CL) after pancreatic surgery have not been established. The aim of the study was to identify an early clinical predictor for CL. Patients and Methods: Fifty-five patients who underwent subtotal stomach preserved pancreaticoduodenectomy (SSPPD) were included. Clinical factors associated with postoperative CL were evaluated. Results: Eleven patients (20%) developed a CL after SSPPD. Shorter operative time, absent pancreatic fistula, and triglyceride output volume at postoperative day (POD) two were independent risk factors for CL. The receiver operating characteristics curve of the daily triglyceride output volume at POD two indicated a cut-off point of 177 mg (AUC=0.782; p=0.004; 95% CI=0.639-0.925). CL was significantly associated with prolonged postoperative hospital stay in patients who did not develop a pancreatic fistula (p=0.003). Conclusion: Daily triglyceride output volume of >177 mg at POD two may be a predictor of CL following pancreaticoduodenectomy.