RT Journal Article SR Electronic T1 Micropapillary Bladder Cancer Metastatic to the Breast: A Case Report and Brief Literature Review JF In Vivo JO In Vivo FD International Institute of Anticancer Research SP 453 OP 459 DO 10.21873/invivo.12278 VO 35 IS 1 A1 ELENA LIEVORE A1 LETTERIO RUNZA A1 MICHELE GHIDINI A1 BARBARA GALASSI A1 ANDREA GALLIOLI A1 CAROLINA BEBI A1 LUCA BOERI A1 CONCETTA BLUNDO A1 CLAUDIA FRANCESCA ROSSI A1 FABRIZIO LONGO A1 GIANCARLO ALBO A1 EMANUELE MONTANARI A1 ELISA DE LORENZIS YR 2021 UL http://iv.iiarjournals.org/content/35/1/453.abstract AB Background: Bladder cancer (BC) usually metastasizes to the lymph nodes, bone, lung, liver and peritoneum, but rarely in the breast. Case Report: We present a case of a 66-year-old female diagnosed with a massive bladder tumor, who presented a right mammary nodule after neo-adjuvant chemotherapy. A biopsy of the nodule did not permit a definite diagnosis of metastatic spread, which was confirmed by excision of the nodule. In the literature, we found only 7 other similar cases of BC metastasis to the breast. Currently, a non-invasive method for differentiating a breast metastasis from primary cancer is lacking, although there are some clinical and radiological aspects that may help the diagnosis. Histological examination provides diagnostic certainty. Conclusion: Breast metastases from BC are unusual and consequently difficult to identify without non-invasive tools. Clinical history and histological study play a pivotal role in determining the correct diagnosis.