RT Journal Article
SR Electronic
T1 Aortitis – An Interdisciplinary Challenge
JF In Vivo
JO In Vivo
FD International Institute of Anticancer Research
SP 41
OP 52
DO 10.21873/invivo.12230
VO 35
IS 1
A1 TETYANA SHCHETYNSKA-MARINOVA
A1 KLAUS AMENDT
A1 MALIHA SADICK
A1 MICHAEL KEESE
A1 MARTIN SIGL
YR 2021
UL http://iv.iiarjournals.org/content/35/1/41.abstract
AB The term ‘aortitis’ comprises a heterogeneous spectrum of diseases, with varied etiology and clinical presentations, whose common characteristic is the inflammation of the aortic wall. Since aortitis can mimic almost all common cardiovascular disorders, its clinical recognition remains a challenge. Some cases of aortitis remain undetected for a long time and may be diagnosed after severe life-threatening complications have already arisen. The diagnosis of aortitis is based on the presence of homogeneous circumferential thickening of the aortic wall detected on aortic imaging, or typical histological features in combination with clinical findings and laboratory parameters. Management of aortitis is usually conservative (immunosuppressive drugs in noninfectious aortitis; antimicrobial drugs in infectious). However, if vascular complications such as aortic aneurysm, rupture, or steno-occlusive events appear, aortic surgery or endovascular therapy may be required. This review article summarizes the current knowledge regarding the etiology, clinical presentation, diagnosis, and treatment of inflammatory diseases of the aorta to promote better clinical management of these entities.