RT Journal Article SR Electronic T1 Culture Separation, Identification and Unique Anti-pathogenic Fungi Capacity of Endophytic Fungi from Gucheng Salvia Miltiorrhiza JF In Vivo JO In Vivo FD International Institute of Anticancer Research SP 325 OP 332 DO 10.21873/invivo.12263 VO 35 IS 1 A1 GUO-KAI WANG A1 JAI-SING YANG A1 YU-FEI HUANG A1 JIN-SONG LIU A1 CHIA-WEN TSAI A1 DA-TIAN BAU A1 WEN-SHIN CHANG YR 2021 UL http://iv.iiarjournals.org/content/35/1/325.abstract AB Background: Salvia miltiorrhiza is a medical herb for human disorders including cardiovascular diseases and cancer. However, the interactions between Salvia miltiorrhiza and its endophytes are largely unknown. The current study aimed at identifying its endophytic fungi and examining their inhibitory effects on anti-pathogenic fungus. Materials and Methods: Distinct species of endophytic fungi were isolated from the roots of Salvia miltiorrhiza, cultured, sequenced, aiming to predict their taxonomical structures. Meanwhile, extracts from each endophytic fungus fermentations were isolated, compared and evaluated on the inhibitory efficacies on five pathological fungi, Cercospora nicotianae, Phoma arachnidicola, Staphylococcus, Phytophthora eggplant, and Rhizoctonia cerealis. Results: A total of 34 strains of endophytic fungi were obtained from Salvia miltiorrhiza. Among them, SX19 and C. Gloeosporioids exhibited the most effective inhibitions on five pathogenic fungi. Conclusion: The anti-fungal activities of the endophytic fungus from Salvia miltiorrhiza were confirmed for the first time, and this may benefit crop quality and production in the future.