PT  - JOURNAL ARTICLE
AU  - GUO-KAI WANG
AU  - JAI-SING YANG
AU  - YU-FEI HUANG
AU  - JIN-SONG LIU
AU  - CHIA-WEN TSAI
AU  - DA-TIAN BAU
AU  - WEN-SHIN CHANG
TI  - Culture Separation, Identification and Unique Anti-pathogenic Fungi Capacity of Endophytic Fungi from Gucheng <em>Salvia Miltiorrhiza</em>
AID  - 10.21873/invivo.12263
DP  - 2021 Jan 01
TA  - In Vivo
PG  - 325--332
VI  - 35
IP  - 1
4099  - http://iv.iiarjournals.org/content/35/1/325.short
4100  - http://iv.iiarjournals.org/content/35/1/325.full
SO  - In Vivo2021 Jan 01; 35
AB  - Background: Salvia miltiorrhiza is a medical herb for human disorders including cardiovascular diseases and cancer. However, the interactions between Salvia miltiorrhiza and its endophytes are largely unknown. The current study aimed at identifying its endophytic fungi and examining their inhibitory effects on anti-pathogenic fungus. Materials and Methods: Distinct species of endophytic fungi were isolated from the roots of Salvia miltiorrhiza, cultured, sequenced, aiming to predict their taxonomical structures. Meanwhile, extracts from each endophytic fungus fermentations were isolated, compared and evaluated on the inhibitory efficacies on five pathological fungi, Cercospora nicotianae, Phoma arachnidicola, Staphylococcus, Phytophthora eggplant, and Rhizoctonia cerealis. Results: A total of 34 strains of endophytic fungi were obtained from Salvia miltiorrhiza. Among them, SX19 and C. Gloeosporioids exhibited the most effective inhibitions on five pathogenic fungi. Conclusion: The anti-fungal activities of the endophytic fungus from Salvia miltiorrhiza were confirmed for the first time, and this may benefit crop quality and production in the future.