RT Journal Article
SR Electronic
T1 Predictors for Grip Strength Loss in Patients With Chronic Liver Diseases
JF In Vivo
JO In Vivo
FD International Institute of Anticancer Research
SP 363
OP 371
DO 10.21873/invivo.12267
VO 35
IS 1
A1 HIROKI NISHIKAWA
A1 KAZUNORI YOH
A1 HIRAYUKI ENOMOTO
A1 NAOTO IKEDA
A1 TOMOYUKI TAKASHIMA
A1 NOBUHIRO AIZAWA
A1 TAKASHI NISHIMURA
A1 SHUHEI NISHIGUCHI
A1 HIROKO IIJIMA
YR 2021
UL http://iv.iiarjournals.org/content/35/1/363.abstract
AB Background/Aim: To elucidate factors associated with secular changes of grip strength (GS) in patients with chronic liver diseases (CLDs) (n=241, 102 males, median age=63 years, 87 liver cirrhosis cases). Materials and Methods: ΔGS (kg/year) was defined as [GS value (second time) – GS value (first time)]/[time interval between the first and second time]. GS loss (GSL) was defined as ΔGS <0 kg/year. Results: The median ΔGS in patients with non-LC, Child-Pugh A (n=70) and Child-Pugh B (n=17) were 0.3, –0.2 and –1.6 kg/year (overall p<0.0001). In the multivariate analysis of factors linked to the GSL for all cases, extracellular water (ECW) to total body water (TBW) ratio was significant (p=0.0007). In the multivariate analysis in male, no significant factor was found, while in female, ECW to TBW ratio was significant (p=0.0024). Conclusion: Liver functional parameters can be closely linked to the GSL especially in female CLD patients.