TY - JOUR T1 - Oncological Outcomes of Pathological T1 Lower Rectal Cancer Patients With or Without Preoperative Chemoradiotherapy JF - In Vivo JO - In Vivo SP - 3559 LP - 3564 DO - 10.21873/invivo.12199 VL - 34 IS - 6 AU - TETSURO TAIRA AU - HIROAKI NOZAWA AU - KAZUSHIGE KAWAI AU - KAZUHITO SASAKI AU - KOJI MURONO AU - MANABU KANEKO AU - SHIGENOBU EMOTO AU - YUUKI IIDA AU - HIROAKI ISHII AU - YUICHIRO YOKOYAMA AU - HIROYUKI ANZAI AU - HIROFUMI SONODA AU - SOICHIRO ISHIHARA Y1 - 2020/11/01 UR - http://iv.iiarjournals.org/content/34/6/3559.abstract N2 - Background/Aim: It remains unclear whether rectal cancers down-staged by preoperative chemoradiotherapy (CRT) have similar prognoses to those of the same stage without preoperative CRT. We compared prognoses of pT1 rectal cancer patients stratified by preoperative CRT. Patients and Methods: We retrieved data of patients with pathological T1 rectal cancer between 2003 and 2020. Patients were divided into the “ypT1 group” who received preoperative CRT following surgery and the “pT1 group” who underwent surgery alone. Factors associated with relapse-free survival (RFS) were investigated. Results: Among 86 patients, ypT1 and pT1 groups comprised 18 and 68 patients, respectively. There was no significant difference in RFS between the groups (p=0.19). Tumor location within 5 cm from the anal verge was associated with recurrence (hazard ratio: 0.13, p=0.034). Conclusion: The prognosis of patients with ypT1 rectal cancer was similar to that of patients with pT1. Low tumor location was a poor prognostic factor. ER -