TY - JOUR T1 - Solitary Fibrous Tumor of the Orbit: A Clinicopathologic Study of Two Cases With Review of the Literature JF - In Vivo JO - In Vivo SP - 3649 LP - 3654 DO - 10.21873/invivo.12211 VL - 34 IS - 6 AU - MIZUHO MITAMURA AU - SATORU KASE AU - YASUO SUZUKI AU - TAKATOSHI SAKAGUCHI AU - YUKA SUIMON AU - YOKO DONG AU - KANAKO C. HATANAKA AU - TOSHIYA SINOHARA AU - MANABU KASE AU - SUSUMU ISHIDA Y1 - 2020/11/01 UR - http://iv.iiarjournals.org/content/34/6/3649.abstract N2 - Background/Aim: Orbital solitary fibrous tumor (SFT) is a rare lesion among orbital tumors, which can be misdiagnosed as another mesenchymal tumor. In this study we report two cases of orbital SFT, focusing on the imaging and pathological findings of the vascular structure inside the tumor. Case Report: A 26-year-old woman and 43-year-old man presented with orbital SFT. The pathological findings revealed a patternless growth pattern of the tumor cells and hemangiopericytoma-like vascularity as well as thickened, dilated blood vessels within the tumor tissue. Tumor cells revealed a diffuse strong positivity for cluster of differentiation 34 (CD34) and signal transducer and activator of transcription 6 (STAT6) in both cases, while B-cell lymphoma 2 (bcl-2) and CD99 were positive in one case. Characteristic findings within the tumor were the arterial components, where a variety of STAT6, CD99 and bcl-2-positive smooth muscle cells were intermingled. Conclusion: Histologically, the tumor tissues might be characterized by not only conventional hemangiopericytoma-like vasculature but also dilated arterial vessels, which were shown to be part of the tumor components. ER -