RT Journal Article
SR Electronic
T1 Clinical Implications of Transbronchial Biopsy for Surgically-resected Non-small Cell Lung Cancer
JF In Vivo
JO In Vivo
FD International Institute of Anticancer Research
SP 691
OP 698
VO 32
IS 3
A1 MOTOAKI YASUKAWA
A1 NORIYOSHI SAWABATA
A1 TAKESHI KAWAGUCHI
A1 NORIKAZU KAWAI
A1 SHIGEKI TANIGUCHI
YR 2018
UL http://iv.iiarjournals.org/content/32/3/691.abstract
AB Background/Aim: Lung biopsies might cause metastasis and/or dissemination. The aim of this study was to review our institutional experience and analyze the outcomes of resection for non-small cell lung cancer (NSCLC), in patients who had received preoperative transbronchial biopsy using fiberoptic bronchoscopy with fluoroscopic imaging (BFS). Patients and Methods: The medical records of consecutive patients between 2010 and 2015 were retrospectively reviewed. Patients were divided into two groups (BFS and Non-BFS). Overall survival (OS) curves and recurrence-free survival (RFS) curves were plotted using the Kaplan–Meier method. Cox regression analyses were used to evaluate the hazard ratio (HR) with the endpoint OS or RFS. Results: We studied the medical records of 531 patients. The 5-year OS rate was 91.8% and 79.8%, in the BFS group and in the Non-BFS group, respectively (p<0.001). BFS was an independent factor associated with RFS HR=2.164 (95%CI=1.399-2.346). Conclusion: Preoperative BFS is a prognostic factor in patients receiving surgery for NSCLC.