@article {YASUKAWA691, author = {MOTOAKI YASUKAWA and NORIYOSHI SAWABATA and TAKESHI KAWAGUCHI and NORIKAZU KAWAI and SHIGEKI TANIGUCHI}, title = {Clinical Implications of Transbronchial Biopsy for Surgically-resected Non-small Cell Lung Cancer}, volume = {32}, number = {3}, pages = {691--698}, year = {2018}, publisher = {International Institute of Anticancer Research}, abstract = {Background/Aim: Lung biopsies might cause metastasis and/or dissemination. The aim of this study was to review our institutional experience and analyze the outcomes of resection for non-small cell lung cancer (NSCLC), in patients who had received preoperative transbronchial biopsy using fiberoptic bronchoscopy with fluoroscopic imaging (BFS). Patients and Methods: The medical records of consecutive patients between 2010 and 2015 were retrospectively reviewed. Patients were divided into two groups (BFS and Non-BFS). Overall survival (OS) curves and recurrence-free survival (RFS) curves were plotted using the Kaplan{\textendash}Meier method. Cox regression analyses were used to evaluate the hazard ratio (HR) with the endpoint OS or RFS. Results: We studied the medical records of 531 patients. The 5-year OS rate was 91.8\% and 79.8\%, in the BFS group and in the Non-BFS group, respectively (p\<0.001). BFS was an independent factor associated with RFS HR=2.164 (95\%CI=1.399-2.346). Conclusion: Preoperative BFS is a prognostic factor in patients receiving surgery for NSCLC.}, issn = {0258-851X}, URL = {https://iv.iiarjournals.org/content/32/3/691}, eprint = {https://iv.iiarjournals.org/content/32/3/691.full.pdf}, journal = {In Vivo} }