RT Journal Article
SR Electronic
T1 Dominant Antibiotic Consumption Patterns Might Be Associated With the Prevalence of Multiple Sclerosis in European Countries
JF In Vivo
JO In Vivo
FD International Institute of Anticancer Research
SP 3467
OP 3472
DO 10.21873/invivo.12186
VO 34
IS 6
A1 GÁBOR TERNÁK
A1 KÁROLY BERÉNYI
A1 GERGELY MÁROVICS
A1 ANDRÁS SÜMEGI
A1 BARBARA FODOR
A1 BALÁZS NÉMETH
A1 ISTVÁN KISS
YR 2020
UL http://iv.iiarjournals.org/content/34/6/3467.abstract
AB Background/Aim: With a prevalence of 50-300 per 100,000 people, about 2.3 million people are estimated to live with multiple sclerosis (MS) globally. The role of antibiotics in the development, or prevention of MS is controversial. We aimed to elucidate the association between antibiotic consumption and MS. Patients and Methods: Pearson statistical comparisons were performed between the annual average antibiotic consumption patterns expressed in Defined Daily Dose/1,000 inhabitants/Day of the antibiotic consumption for the years of 1997-2018 in 30 European countries, with the respective prevalence of MS estimated for 2016. Results: A positive correlation (promoting effect) has been observed between narrow spectrum penicillin (r=0.636) and tetracycline (r=0.412) consumption with MS prevalence. Conclusion: Countries, with high consumption of narrow spectrum penicillin and tetracycline, experience a higher prevalence of MS than other countries.