PT  - JOURNAL ARTICLE
AU  - IOANNIS D. KOSTAKIS
AU  - THEMISTOKLIS FERETIS
AU  - CHRISTOS DAMASKOS
AU  - NIKOLAOS GARMPIS
AU  - GEORGE LIAPIS
AU  - IOANNIS PATERAS
AU  - ANNA GARMPI
AU  - VASILIKI E. GEORGAKOPOULOU
AU  - EFSTATHIOS A. ANTONIOU
TI  - Nuchal-type Fibroma: Single-Center Experience and Systematic Literature Review
AID  - 10.21873/invivo.12032
DP  - 2020 Sep 01
TA  - In Vivo
PG  - 2217--2223
VI  - 34
IP  - 5
4099  - http://iv.iiarjournals.org/content/34/5/2217.short
4100  - http://iv.iiarjournals.org/content/34/5/2217.full
SO  - In Vivo2020 Sep 01; 34
AB  - Background: Nuchal-type fibroma is a rare benign tumor arising from the connective tissue. Our aim was to present our experience via two cases of this tumor and a comprehensive review of the literature. Patients and Methods: We report a case of a 23-year-old female with a mass located in the posterior neck and the upper back and a case of a 50-year-old male with a mass located in the posterior neck, which were proved to be nuchal-type fibromas in the histopathological examination. We also searched the PubMed/Medline database for published cases of nuchal-type fibromas. Results and Discussion: Nuchal-type fibroma is a rare benign tumor arising from the connective tissue, usually in the posterior neck, which affects different ages, with most patients being male. It is a poorly circumscribed tumor consisting of hypocellular, thick, dense and haphazardly arranged collagen bundles with entrapped adipocytes, nerve fibers and muscle fascicles and a few scattered spindle cells, which are CD34 positive. Its excision is curative, and the recurrence risk is generally low. However, patients with Gardner's syndrome may experience recurrence more frequently. Conclusion: Nuchal-type fibroma should be included in the differential diagnosis of subcutaneous, soft-tissue masses, especially when these involve the posterior neck.