RT Journal Article
SR Electronic
T1 A Feasibility Study for 3D-printed Poly(methyl methacrylate)-resin Tracheostomy Tube Using a Hamster Cheek Pouch Model
JF In Vivo
JO In Vivo
FD International Institute of Anticancer Research
SP 1749
OP 1758
DO 10.21873/invivo.11968
VO 34
IS 4
A1 HARRY JUNG
A1 JI SEUNG LEE
A1 JUN HO LEE
A1 KI JOON PARK
A1 JAE JUN LEE
A1 HAE SANG PARK
YR 2020
UL http://iv.iiarjournals.org/content/34/4/1749.abstract
AB Background/Aim: A three-dimensional (3D) printed tracheostomy tube has potential application for patients who require a specialized tube. The aim of this study was to evaluate the characteristics of various 3D printing materials and determine their use in producing 3D-printed tracheostomy tube. Materials and Methods: Mechanical, chemical, and microbiological in vivo changes in the scaffolds were analyzed using a hamster cheek pouch (HCP) model. Results: The poly methyl methacylate (PMMA)-resin showed superior pre- and post-insertion mechanical properties and a relatively consistent lower biofilm formation compared with other scaffolds. PMMA-resin was successfully 3D-printed with dimensional accuracy without a support system. The use of a 3D-printed PMMA tracheostomy tube in a rabbit trachea showed no definite signs of infection, allergy or foreign body reaction. Conclusion: PMMA-resin can be proposed as an alternative for a 3D-printed tracheostomy tube material. In addition, we suggest HCPs as an in vivo model for evaluating indwelling medical devices.