TY - JOUR T1 - A Feasibility Study for 3D-printed Poly(methyl methacrylate)-resin Tracheostomy Tube Using a Hamster Cheek Pouch Model JF - In Vivo JO - In Vivo SP - 1749 LP - 1758 DO - 10.21873/invivo.11968 VL - 34 IS - 4 AU - HARRY JUNG AU - JI SEUNG LEE AU - JUN HO LEE AU - KI JOON PARK AU - JAE JUN LEE AU - HAE SANG PARK Y1 - 2020/07/01 UR - http://iv.iiarjournals.org/content/34/4/1749.abstract N2 - Background/Aim: A three-dimensional (3D) printed tracheostomy tube has potential application for patients who require a specialized tube. The aim of this study was to evaluate the characteristics of various 3D printing materials and determine their use in producing 3D-printed tracheostomy tube. Materials and Methods: Mechanical, chemical, and microbiological in vivo changes in the scaffolds were analyzed using a hamster cheek pouch (HCP) model. Results: The poly methyl methacylate (PMMA)-resin showed superior pre- and post-insertion mechanical properties and a relatively consistent lower biofilm formation compared with other scaffolds. PMMA-resin was successfully 3D-printed with dimensional accuracy without a support system. The use of a 3D-printed PMMA tracheostomy tube in a rabbit trachea showed no definite signs of infection, allergy or foreign body reaction. Conclusion: PMMA-resin can be proposed as an alternative for a 3D-printed tracheostomy tube material. In addition, we suggest HCPs as an in vivo model for evaluating indwelling medical devices. ER -