PT - JOURNAL ARTICLE AU - HARRY JUNG AU - JI SEUNG LEE AU - JUN HO LEE AU - KI JOON PARK AU - JAE JUN LEE AU - HAE SANG PARK TI - A Feasibility Study for 3D-printed Poly(methyl methacrylate)-resin Tracheostomy Tube Using a Hamster Cheek Pouch Model AID - 10.21873/invivo.11968 DP - 2020 Jul 01 TA - In Vivo PG - 1749--1758 VI - 34 IP - 4 4099 - http://iv.iiarjournals.org/content/34/4/1749.short 4100 - http://iv.iiarjournals.org/content/34/4/1749.full SO - In Vivo2020 Jul 01; 34 AB - Background/Aim: A three-dimensional (3D) printed tracheostomy tube has potential application for patients who require a specialized tube. The aim of this study was to evaluate the characteristics of various 3D printing materials and determine their use in producing 3D-printed tracheostomy tube. Materials and Methods: Mechanical, chemical, and microbiological in vivo changes in the scaffolds were analyzed using a hamster cheek pouch (HCP) model. Results: The poly methyl methacylate (PMMA)-resin showed superior pre- and post-insertion mechanical properties and a relatively consistent lower biofilm formation compared with other scaffolds. PMMA-resin was successfully 3D-printed with dimensional accuracy without a support system. The use of a 3D-printed PMMA tracheostomy tube in a rabbit trachea showed no definite signs of infection, allergy or foreign body reaction. Conclusion: PMMA-resin can be proposed as an alternative for a 3D-printed tracheostomy tube material. In addition, we suggest HCPs as an in vivo model for evaluating indwelling medical devices.