RT Journal Article
SR Electronic
T1 Salvage Photon or Proton Radiotherapy for Oligo-recurrence in Regional Lymph Nodes After Surgery for Non-small Cell Lung Cancer
JF In Vivo
JO In Vivo
FD International Institute of Anticancer Research
SP 1883
OP 1892
DO 10.21873/invivo.11984
VO 34
IS 4
A1 NAKAMURA, MASATOSHI
A1 OHNISHI, KAYOKO
A1 ISHIKAWA, HITOSHI
A1 NAKAZAWA, KENSUKE
A1 SHIOZAWA, TOSHIHIRO
A1 OKUMURA, TOSHIYUKI
A1 SEKINE, IKUO
A1 SATO, YUKIO
A1 HIZAWA, NOBUYUKI
A1 SAKURAI, HIDEYUKI
YR 2020
UL http://iv.iiarjournals.org/content/34/4/1883.abstract
AB Background/Aim: To evaluate the outcome of definitive salvage radiotherapy (RT) in non-small cell lung cancer (NSCLC) patients with oligo-recurrence in regional lymph nodes after surgery. Patients and Methods: Between January 2003 and December 2016, 33 patients with NSCLC were reviewed from radiotherapy database at our hospital. All patients received photon or proton salvage RT for metastases in the regional lymph nodes. Results: The median follow-up from salvage RT was 35.2 (range=5.9-89.6) months. Recurrences occurred in 18 (55%) patients, and the 3-year overall and progression-free survival rates were 63.8% and 45.1%, respectively. Regional and local control improved patients' survival and these control rates were increased by use of concurrent chemotherapy (p=0.039) and proton RT (p=0.084). No grade 4 acute or late non-hematologic toxicities were observed. Conclusion: Salvage RT is an effective treatment for NSCLC patients with oligo-recurrence at regional lymph nodes.