RT Journal Article
SR Electronic
T1 Hysterectomy for Recurrent/Residual Cervical Cancer Following Definitive Radiotherapy
JF In Vivo
JO In Vivo
FD International Institute of Anticancer Research
SP 2173
OP 2177
DO 10.21873/invivo.12026
VO 34
IS 4
A1 NAKASONE, TADAHARU
A1 TAIRA, YUSUKE
A1 SHIMOJI, YUKO
A1 ARAKAKI, YOSHIHISA
A1 NAKAMOTO, TOMOKO
A1 OOYAMA, TAKUMA
A1 KUDAKA, WATARU
A1 KANESHIMA, ITOMI
A1 NISHIHIRA, KUMIKO
A1 MEKARU, KEIKO
A1 AOKI, YOICHI
YR 2020
UL http://iv.iiarjournals.org/content/34/4/2173.abstract
AB Background/Aim: Radical hysterectomy has been used for local recurrent or persistent (LR) cervical cancer after radiotherapy (RT), but the rate of serious complications is high and tolerance is low. This study determined the efficacy, safety, and prognostic factors of adjuvant simple hysterectomy in LR cervical cancer post-RT. Patients and Methods: A total of 21 patients who underwent hysterectomy for LR cervical cancer post-RT in our Department between May 2007 and September 2018 were included in the study. Primary, definitive RT was performed. Histological response by definitive RT in the extirpated uterus was classified on the basis of histological response criteria: effect (Ef) 0-3. Results: The 5-year overall survival (OS) and disease-free survival (DFS) rates were 51.9% and 50.1%, respectively. Ef 1 was significantly associated with poorer prognosis compared to Ef 2 or Ef 3. Conclusion: Adjuvant hysterectomy could be a treatment of choice for LR cervical cancer post-RT.