TY - JOUR T1 - Quantitative Assessment of Interim PET/CT Could Have More Prognostic Relevance than Visual Assessment for Predicting Clinical Outcome of Extranodal Diffuse Large B Cell Lymphoma JF - In Vivo JO - In Vivo SP - 2127 LP - 2134 DO - 10.21873/invivo.12018 VL - 34 IS - 4 AU - DONG WON BAEK AU - HEE JEONG CHO AU - JU-HYUNG KIM AU - SANG KYUN SOHN AU - GA-YOUNG SONG AU - SEO-YEON AHN AU - SUNG-HOON JUNG AU - JAE SOOK AHN AU - JE-JUNG LEE AU - HYEOUNG-JOON KIM AU - SHIN-YOUNG JEONG AU - CHAE MOON HONG AU - JUNG-JOON MIN AU - JOON-HO MOON AU - DEOK-HWAN YANG Y1 - 2020/07/01 UR - http://iv.iiarjournals.org/content/34/4/2127.abstract N2 - Background/Aim: The present study retrospectively investigated the predictive accuracy of interim positron emission tomography/computed tomography (iPET/CT) based on the Deauville 5-point scale (5-PS) and a quantitative SUV-based assessment in patients with extranodal (EN) diffuse large B cell lymphoma (DLBCL). Patients and Methods: The Deauville 5-PS and the SUVmax reduction (ΔSUVmax) assessment for interpreting the response to iPET/CT were used. Results: A total of 163 patients were enrolled in this study. With a median follow-up of 52.5 months, ΔSUVmax successfully predicted the survival outcomes of patients with one extranodal (EN) involvement in terms of overall survival (OS) (p=0.012) and progression-free survival (PFS) (p<0.001). Visual assessment using the Deauville 5-PS did not predict survival outcomes in patients with one or more EN involvements in terms of OS and PFS. Conclusion: The quantitative SUV-based assessment with iPET/CT was a significant prognosticator for long-term survival outcomes, especially in patients with one EN involvement. ER -