PT - JOURNAL ARTICLE AU - LUCA GIANNELLA AU - MATTEO SERRI AU - ELENA MACCARONI AU - JACOPO DI GIUSEPPE AU - GIOVANNI DELLI CARPINI AU - ROSSANA BERARDI AU - FRANCESCO SOPRACORDEVOLE AU - ANDREA CIAVATTINI TI - Endometriosis-associated Clear Cell Carcinoma of the Abdominal Wall After Caesarean Section: A Case Report and Review of the Literature AID - 10.21873/invivo.12021 DP - 2020 Jul 01 TA - In Vivo PG - 2147--2152 VI - 34 IP - 4 4099 - http://iv.iiarjournals.org/content/34/4/2147.short 4100 - http://iv.iiarjournals.org/content/34/4/2147.full SO - In Vivo2020 Jul 01; 34 AB - Background/Aim: Clear cell carcinoma of the abdominal wall is a sporadic event. To date, about thirty cases have been reported in the literature. This article provides a case report and literature review of an infrequent occurrence with poor prognosis. Case Report: A 45-year-old woman with pelvic pain and an abdominal mass came to our attention. Her medical history was notable for two previous cesarean sections. Physical examination revealed a smooth, multilocular mass measuring about 20 cm, arising from the previous surgical scar. Histology revealed clear-cell carcinoma resulting from the transformation of abdominal wall endometriosis. Given the disease extent, the patient underwent front-line chemotherapy. After several and multiple chemotherapy regimens, there was a disease progression that resulted in the death of the patient in 7 months. The literature review showed that a previous cesarean section was present in 91% of cases. Besides, approximately 26.5% of women died within 12 months of being diagnosed. The mean age of women was 45.88 years, while the average size of the lesion was 11 cm. Conclusion: Clear cell carcinoma is a rare but occurring event. Middle-aged women showing an abdominal wall mass in close relation with a surgical scar from a previous cesarean section must be promptly investigated. Treatment options usually include surgery and chemotherapy with poor results.