RT Journal Article SR Electronic T1 Breast Cancer and COVID-19: The Effect of Fear on Patients' Decision-making Process JF In Vivo JO In Vivo FD International Institute of Anticancer Research SP 1651 OP 1659 DO 10.21873/invivo.11957 VO 34 IS 3 suppl A1 GIANLUCA VANNI A1 MARCO MATERAZZO A1 MARCO PELLICCIARO A1 SARA INGALLINELLA A1 MAURIZIO RHO A1 FRANCESCA SANTORI A1 MARIA COTESTA A1 JONATHAN CASPI A1 ANNA MAKAROVA A1 CHIARA ADRIANA PISTOLESE A1 ORESTE CLAUDIO BUONOMO YR 2020 UL http://iv.iiarjournals.org/content/34/3_suppl/1651.abstract AB Background/Aim: Coronavirus-19 (COVID-19) pandemic outbreak is currently having a huge impact on medical resource allocation. Breast Cancer (BC) patients are concerned both with BC treatment and COVID-19. This study aimed to estimate the impact of anxiety among patients, caused by the spreading of COVID-19. Patients and Methods: Between the 16th of January and the 20th of March 2020, we retrospectively enrolled 160 patients. Eighty-two patients with a suspected breast lesion (SBL) were divided into two groups: PRE-COVID-19-SBL and POST-COVID-19-SBL. Seventy-eight BC patients were divided into PRE-COVID-19-BC and POST-COVID-19-BC. Patient characteristics including age, marital status, SBL/BC diameter, personal and family history of BC, clinical stage and molecular subtype were recorded. Procedure Refusal (PR) and Surgical Refusal (SR) were also recorded with their reason. Results: BC and SBL analysis showed no difference in pre-treatment characteristics (p>0.05). Both POST-COVID-19-SBL and POST-COVID-19-BC groups showed higher rates of PR and SR (p=0.0208, p=0.0065 respectively). Infection risk represented primary reason for refusal among POST-COVID-19 patients. Conclusion: COVID-19-related anxiety could affect patients' decision-making process.