TY - JOUR T1 - Does Age Matter? Estimating Risks of Locoregional Recurrence After Breast-conservative Surgery JF - In Vivo JO - In Vivo SP - 1125 LP - 1132 DO - 10.21873/invivo.11884 VL - 34 IS - 3 AU - GIANLUCA VANNI AU - MARCO MATERAZZO AU - MARCO PELLICCIARO AU - LJUBA MORANDO AU - ILARIA PORTARENA AU - LUCIA ANEMONA AU - MARIA ROLANDO D'ANGELILLO AU - ROSARIA BARBARINO AU - AGOSTINO CHIARAVALLOTI AU - ROSARIA MEUCCI AU - TOMMASO PERRETTA AU - CAMILLA DEIANA AU - PAOLO ORSARIA AU - JONATHAN CASPI AU - CHIARA ADRIANA PISTOLESE AU - ORESTE CLAUDIO BUONOMO Y1 - 2020/05/01 UR - http://iv.iiarjournals.org/content/34/3/1125.abstract N2 - Background/Aim: In 2016, in the United States, more than 50% of breast cancer (BC) cases were diagnosed in patients older than 60 years of age. Our study aimed to estimate the risk of locoregional recurrence (LR) in patients who underwent breast-conservative treatment (BCT), according to age. Patients and Methods: This retrospective monocentric study analyzed 613 cases of patients who underwent BCT between 2003 and 2014. Patients were divided into groups according to age: Under70 (under 70 years old) and Over70 (above 70 years old). Margins width, histology results, prognostic and predictive factors were compared. Subgroup analysis was performed for patients who experienced LR. Results: LR Incidence among Under70 and Over70 was 5.4% and 1.7%, respectively (p<0.01). Group Over70 is characterized by larger tumors and a lower Ki67 index (p<0.01). Conclusion: Operation time reduction, better aesthetic results and reduced LR risk support BCT. The Over70 group exhibited better outcomes in terms of LR despite larger tumor dimensions. ER -