RT Journal Article
SR Electronic
T1 Estimating the Lifespan of Elderly Patients With Cerebral Metastases from Kidney Cancer
JF In Vivo
JO In Vivo
FD International Institute of Anticancer Research
SP 1321
OP 1324
DO 10.21873/invivo.11908
VO 34
IS 3
A1 DIRK RADES
A1 TRANG NGUYEN
A1 STEVEN E. SCHILD
YR 2020
UL http://iv.iiarjournals.org/content/34/3/1321.abstract
AB Background/Aim: Outcomes of elderly patients with cerebral metastases from kidney cancer may be improved by personalized treatment. A scoring instrument for estimating survival in these patients is presented. Patients and Methods: Twenty-four elderly kidney cancer patients receiving whole-brain irradiation (WBI) were retrospectively investigated. WBI-regimen and six pre-treatment factors were evaluated including age, gender, performance score, number of cerebral metastases, extracranial metastases and time from kidney cancer diagnosis to WBI. Results: Number of cerebral metastases (p=0.194) and time from kidney cancer diagnosis to WBI (p=0.107) correlated with survival and were included in the instrument. Based on these factors, patient scores of 0, 1 and 2 points resulted in 6-month survival rates of 0%, 15% and 60% (p=0.131), respectively. Two groups were designed, 0-1 and 2 points, with 6-month survival rates of 11% and 60% (p=0.108), respectively. Conclusion: This new instrument can assist physicians aiming to estimate a patient's survival prognosis to provide personalized treatment.