TY - JOUR T1 - Association of an Overhydrated State With the Liver Fibrosis and Prognosis of Cirrhotic Patients JF - In Vivo JO - In Vivo SP - 1347 LP - 1353 DO - 10.21873/invivo.11912 VL - 34 IS - 3 AU - KYOHEI KISHINO AU - HIRAYUKI ENOMOTO AU - YOSHIHIRO SHIMONO AU - EI-ICHIRO MORIWAKI AU - HIROKI NISHIKAWA AU - TAKASHI NISHIMURA AU - YOSHINORI IWATA AU - HIROKO IIJIMA AU - SHUHEI NISHIGUCHI Y1 - 2020/05/01 UR - http://iv.iiarjournals.org/content/34/3/1347.abstract N2 - Background/Aim: A bioimpedance analysis (BIA) can indicate an overhydrated state as the extracellular water/total body water (ECW/TBW) value. This study aimed to assess the clinical significance of this value in patients with chronic liver diseases (CLDs). Patients and Methods: A total of 552 CLD patients who received a liver biopsy and underwent anthropometric assessment and BIA-based body composition analysis were enrolled. The association of the ECW/TBW value with the liver fibrosis and nutritional status was assessed. The relationship between the ECW/TBW value and the prognosis of cirrhotic patients (N=209) was also evaluated. Results: The ECW/TBW value increased as liver fibrosis progressed and was also related to decreased muscle mass/sarcopenia. The presence of overhydration was associated with a poor prognosis of cirrhotic patients. Conclusion: An increased ECW/TBW value was associated with progressive liver fibrosis and malnutrition and related to the prognosis of cirrhotic patients. ER -