TY - JOUR T1 - Metastatic Cutaneous Squamous Cell Carcinoma in Liver Successfully Treated With Partial Hepatectomy and Adjuvant Irinotecan Chemotherapy JF - In Vivo JO - In Vivo SP - 825 LP - 828 DO - 10.21873/invivo.11844 VL - 34 IS - 2 AU - YASUHIKO ASAHINA AU - YOSHIO NAKAMURA AU - KEIJI TANESE AU - IKUKO HIRAI AU - KEITARO FUKUDA AU - MASAYUKI AMAGAI AU - TAKERU FUNAKOSHI Y1 - 2020/03/01 UR - http://iv.iiarjournals.org/content/34/2/825.abstract N2 - Background: The management of distant metastatic cutaneous squamous cell carcinoma (cSCC) relies mainly on chemotherapies and radiotherapy. Management of patients with cSCC with surgically resectable distant metastatic lesions is not clear. Case Report: A 59-year-old male had 4×10 cm-sized cSCC on the perianal skin with inguinal lymph node metastasis. Surgical resection was performed followed by radiation and adjuvant carboplatin and farmorubicin combination therapy. Six months later, 25 mm-sized solitary metastatic nodule arose on the liver. Base on his favorable overall condition fulfilling the criteria of tumor resectability for the treatment of tumors in liver and having good performance status, laparoscopic partial hepatectomy and six courses of adjuvant irinotecan therapy were performed. The surgical margin was negative and the patient has maintained complete remission for over 3 years. Conclusion: The clinical course of the present case suggests that surgical approaches should also be considered as candidate additional therapy for resectable distant metastatic cSCC. ER -