PT - JOURNAL ARTICLE AU - HIROYUKI YOSHINO AU - AKIRA HASUIKE AU - NAOYA SANJO AU - DAISUKE SATO AU - TATSUYA KUBOTA AU - HIDEKAZU NAGASHIMA AU - SHUICHI SATO TI - CO<sub>2</sub> Laser De-epithelization Technique for Subepithelial Connective Tissue Graft: A Study of 21 Recessions AID - 10.21873/invivo.11851 DP - 2020 Mar 01 TA - In Vivo PG - 869--875 VI - 34 IP - 2 4099 - http://iv.iiarjournals.org/content/34/2/869.short 4100 - http://iv.iiarjournals.org/content/34/2/869.full SO - In Vivo2020 Mar 01; 34 AB - Background/Aim: To report cases in which we achieved sufficient width of the keratinized gingiva using a coronally advanced flap in combination with a subepithelial connective tissue graft (SCTG) obtained by the ‘CO2 laser de-epithelization technique’ (CODE). Patients and Methods: Eleven patients with 21 Miller Class I, II, and III gingival recessions had surgery. To prepare SCTG, free gingival grafts were harvested and de-epithelialized extra-orally. De-epithelialization was conducted by irradiation of CO2 laser. Postoperative examinations were performed at 12 months. Results: At 12 months, statistically highly significant root coverage was achieved in all recessions. Complete root coverage was obtained in 7 of the 21 recessions. The treatment yielded mean root coverage of 41.0%, and was associated with a mean gain of keratinized gingiva of 2.9±0.3 mm. Conclusion: The use of CODE allows harvesting grafts of excellent quality and quantity and increases the keratinization of the overlying mucosal epithelium.