RT Journal Article SR Electronic T1 Differences in Risk Factors for Melanoma in Young and Middle-aged Higher-risk Patients JF In Vivo JO In Vivo FD International Institute of Anticancer Research SP 703 OP 708 DO 10.21873/invivo.11827 VO 34 IS 2 A1 JOHANNA S. PALVE A1 NIINA J. KORHONEN A1 TIINA H. LUUKKAALA A1 MINNA T. KÄÄRIÄINEN YR 2020 UL http://iv.iiarjournals.org/content/34/2/703.abstract AB Background/Aim: Differences in risk factors for melanoma between young adults (18-39 years) and middle-aged (40-60 years) are not well documented. In this study, we aimed to determine differences in risk factors and characteristics of melanoma between these groups. Patients and Methods: This retrospective study is a review on 330 patients, including 250 middle-aged and 80 young adults, during the period 2006-2016 in the Tampere university hospital, in Finland. Results: Forty-one per cent of middle-aged and 47% of young adults were defined as higher-risk patients. High nevus count was the most common host risk factor in both groups. Young were more likely to have a family history of melanoma. Middle-aged had more often excessive intermittent sun exposure and a history of sunburn. Host risk characteristics were less commonly associated with thicker melanomas. Conclusion: A high number of patients have host risk factors for melanoma. Several differences exist in risk factors and characteristics of melanomas between young adults and middle-aged patients.