RT Journal Article SR Electronic T1 A Novel Multi-faceted Course Blueprint to Support Outcome-based Holistic Surgical Education: The Integrated Generation 4 Model (iG4) JF In Vivo JO In Vivo FD International Institute of Anticancer Research SP 503 OP 509 DO 10.21873/invivo.11801 VO 34 IS 2 A1 SIDERIS, MICHAIL A1 PAPALOIS, VASSILIOS A1 ATHANASIOU, THANOS A1 PAPAGRIGORIADIS, SAVVAS A1 PIERIDES, MICHAEL A1 VELMAHOS, GEORGE A1 PAPALOIS, APOSTOLOS YR 2020 UL http://iv.iiarjournals.org/content/34/2/503.abstract AB Background/Aim: We present a novel multi-faceted, internationally adaptable course curriculum blueprint, which provides holistic surgical education at the undergraduate level. Materials and Methods: The Integrated Generation 4 (iG4) course (Essential Skills in the Management of Surgical Cases – ESMSC Marathon course) curriculum consists of four essential learning components: core skills-based learning, case-based discussions, basic science workshops and soft-skills. These are all clustered in a specialty-led network architecture. Every cluster consists of modules from the four learning cores, while network nodes are modules that are mutually shared by more than one clusters. Results: We produced a standardized blueprint of 50 modules based on the 4 learning cores, covering 9 surgical specialties. This resulted in a curriculum map where every module is described using 3 parameters: χ axis (skills component), y axis (knowledge component), z axis (specialty component). Conclusion: iG4 proof of concept sets the ground for a novel, reproducible and standardised effort to produce a portfolio of undergraduate surgical skills serving the vision of holistic surgical education.