RT Journal Article
SR Electronic
T1 Pelvic Exenteration for Locally Advanced and Relapsed Pelvic Malignancies – An Analysis of 100 Cases
JF In Vivo
JO In Vivo
FD International Institute of Anticancer Research
SP 2205
OP 2210
DO 10.21873/invivo.11723
VO 33
IS 6
A1 NICOLAE BACALBASA
A1 IRINA BALESCU
A1 MIHAELA VILCU
A1 ADRIAN NEACSU
A1 SIMONA DIMA
A1 ADINA CROITORU
A1 IULIAN BREZEAN
YR 2019
UL http://iv.iiarjournals.org/content/33/6/2205.abstract
AB Background/Aim: Although pelvic exenteration is an aggressive surgical procedure, it remains almost the only curative solution for patients diagnosed with large pelvic malignancies. Patients and Methods: We present a series of 100 patients submitted to pelvic exenteration with curative intent. Results: The origin of the primary tumor was most commonly represented by cervical cancer, followed by, endometrial cancer, rectal cancer, ovarian cancer and vulvo-vaginal cancer. An R0 resection was confirmed in 68 cases, while the remaining 32 cases presented lateral positive resection margins or perineal positive margins. The postoperative morbidity rate was 37% while the mortality rate was 3%. As for the-long term outcomes, the median overall survival time was 38.7 months, being most significantly influenced by the origin of the primary tumor. Conclusion: Although pelvic exenteration is still associated with an increased morbidity, an important improvement in the long-term survival can be achieved, especially if radical resection is feasible.