TY - JOUR T1 - Distribution of Solitary and Multiple Enchondromas of the Hand JF - In Vivo JO - In Vivo SP - 2235 LP - 2240 DO - 10.21873/invivo.11728 VL - 33 IS - 6 AU - SHINJI MIWA AU - HIDEKI OKAMOTO AU - SATOSHI YAMADA AU - YOHEI KAWAGUCHI AU - KOJIRO ENDO AU - HISAKI AIBA AU - KATSUHIRO HAYASHI AU - HIROAKI KIMURA AU - ISATO SEKIYA AU - TAKANOBU OTSUKA AU - HIROYUKI TSUCHIYA Y1 - 2019/11/01 UR - http://iv.iiarjournals.org/content/33/6/2235.abstract N2 - Background/Aim: Although some patients with enchondroma have multiple lesions, no study has investigated the distribution of lesions in patients with multiple enchondromas. Patients and Methods: This retrospective study included 118 patients with enchondroma of the hand. The incidence and characteristic feature of multiple enchondromas of the hand were investigated. Results: Four patients (3.4%) had multiple enchondromas. In all the patients with multiple enchondromas, the lesions occurred in the middle phalanx, proximal phalanx, and metacarpal bone in the same digital ray. Conclusion: The development of the hand rapidly progresses from intrauterine day 33 to day 54. The digital rays are evident on intrauterine day 41, and separation of the distal phalanx, middle phalanx, proximal phalanx, and metacarpal bone is completed until intrauterine day 54. The successive occurrence of multiple enchondroma lesions in the same digital ray in all four cases suggests that the occurrence of lesions preceded the separation of the hand bones and the lesions were divided during the development of these bones. ER -