%0 Journal Article %A RICCARDO ARISIO %A FULVIO BORELLA %A MAURO PORPIGLIA %A ANTONIO DURANDO %A ROBERTO BELLINO %A MARIA GRAZIA BAU %A CORRADO DE SANCTIS %A SAVERIO DANESE %A CHIARA BENEDETTO %A DIONYSSIOS KATSAROS %T Axillary Dissection vs. no Axillary Dissection in Breast Cancer Patients With Positive Sentinel Lymph Node: A Single Institution Experience %D 2019 %R 10.21873/invivo.11689 %J In Vivo %P 1941-1947 %V 33 %N 6 %X Background/Aim: Axillary surgery of breast cancer patients is undergoing a paradigm shift, as axillary lymph node dissection's (ALND) usefulness is being questioned in the treatment of patients with tumor-positive sentinel lymph node biopsy (SLNB). The aim of this study was to investigate the overall survival (OS) and relapse-free survival (RFS) of patients with positive SLNB treated with ALND or not. Patients and Methods: We investigated 617 consecutive patients with cN0 operable breast cancer with positive SLNB undergoing mastectomy or conservative surgery. A total of 406 patients underwent ALND and 211 were managed expectantly. Results: No significant difference in OS and RFS was found between the two groups. The incidence of loco-regional recurrence in the SLNB-only group and the ALND group was low and not significant. Conclusion: The type of breast cancer surgery and the omission of ALND does not improve OS or RSF rate in cases with metastatic SLN. %U https://iv.iiarjournals.org/content/invivo/33/6/1941.full.pdf