RT Journal Article
SR Electronic
T1 Pneumococcal Vaccination Strategies Among HIV-infected Adult Patients: A Review of the Literature
JF In Vivo
JO In Vivo
FD International Institute of Anticancer Research
SP 1425
OP 1430
DO 10.21873/invivo.11620
VO 33
IS 5
A1 ANNA GARMPI
A1 CHRISTOS DAMASKOS
A1 NIKOLAOS GARMPIS
A1 ALEXANDROS PATSOURAS
A1 SPYRIDON SAVVANIS
A1 NIKOLAOS GRAVVANIS
A1 EVANGELOS DIAMANTIS
YR 2019
UL http://iv.iiarjournals.org/content/33/5/1425.abstract
AB Background/Aim: Streptococcus pneumoniae is the leading cause of bacterial pneumonia and an important cause of invasive disease. Despite the antiretroviral therapies, adults infected with human immunodeficiency virus (HIV) are at particular risk for invasive pneumococcal disease (IPD). The purpose of this study was to report the efficacy of the strategies currently being used in pneumococcal vaccination for HIV-infected adults. Materials and Methods: A literature search was performed through electronic databases, for original articles in English, from years 2000 to 2019. Clinical trials controlled or randomized, and cohort studies were included. Results: While 23-valent pneumococcal polysaccharide vaccine (PPV23) is recommended for immunocompromised patients, it has been reported that it is less suitable for HIV-infected patients. Recent guidelines have added pneumococcal conjugate vaccine (PCV) to the list of recommended vaccines. Conclusion: Further studies are needed to determine the optimal vaccines and intervals for subsequent revaccinations during the lifetime.