TY - JOUR T1 - Pneumococcal Vaccination Strategies Among HIV-infected Adult Patients: A Review of the Literature JF - In Vivo JO - In Vivo SP - 1425 LP - 1430 DO - 10.21873/invivo.11620 VL - 33 IS - 5 AU - ANNA GARMPI AU - CHRISTOS DAMASKOS AU - NIKOLAOS GARMPIS AU - ALEXANDROS PATSOURAS AU - SPYRIDON SAVVANIS AU - NIKOLAOS GRAVVANIS AU - EVANGELOS DIAMANTIS Y1 - 2019/09/01 UR - http://iv.iiarjournals.org/content/33/5/1425.abstract N2 - Background/Aim: Streptococcus pneumoniae is the leading cause of bacterial pneumonia and an important cause of invasive disease. Despite the antiretroviral therapies, adults infected with human immunodeficiency virus (HIV) are at particular risk for invasive pneumococcal disease (IPD). The purpose of this study was to report the efficacy of the strategies currently being used in pneumococcal vaccination for HIV-infected adults. Materials and Methods: A literature search was performed through electronic databases, for original articles in English, from years 2000 to 2019. Clinical trials controlled or randomized, and cohort studies were included. Results: While 23-valent pneumococcal polysaccharide vaccine (PPV23) is recommended for immunocompromised patients, it has been reported that it is less suitable for HIV-infected patients. Recent guidelines have added pneumococcal conjugate vaccine (PCV) to the list of recommended vaccines. Conclusion: Further studies are needed to determine the optimal vaccines and intervals for subsequent revaccinations during the lifetime. ER -