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Open Access

Management of a Complex Orbital Post-transplantation Lymphoproliferative Disorder: A Case Report and Literature Review

TESSHO MARUYAMA, YOHEI HOKAMA, KAZUTAKA KISHABA, TOMOMI KUNINAKA, SHIGETAKA KOBAYASHI, HIDEKI NAGAMINE, HIROFUMI MIYAHIRA, KEI TANAKA, KAZUHO MORICHIKA, FUMI KAWAKAMI, MARIKO TOMITA, NAOKI WADA, AKIRA YOGI, HIROAKI MASUZAKI and TADASHI HAMASAKI
In Vivo May 2026, 40 (3) 1824-1831; DOI: https://doi.org/10.21873/invivo.14336
TESSHO MARUYAMA
1Comprehensive Health Professions Education Center, University of the Ryukyus Hospital, Okinawa, Japan;
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  • For correspondence: h075324{at}cs.u-ryukyu.ac.jp tesshou.730{at}gmail.com
YOHEI HOKAMA
2Department of Neurosurgery, University of the Ryukyus Hospital, Okinawa, Japan;
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KAZUTAKA KISHABA
2Department of Neurosurgery, University of the Ryukyus Hospital, Okinawa, Japan;
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TOMOMI KUNINAKA
2Department of Neurosurgery, University of the Ryukyus Hospital, Okinawa, Japan;
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SHIGETAKA KOBAYASHI
2Department of Neurosurgery, University of the Ryukyus Hospital, Okinawa, Japan;
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HIDEKI NAGAMINE
2Department of Neurosurgery, University of the Ryukyus Hospital, Okinawa, Japan;
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HIROFUMI MIYAHIRA
3Department of Diagnostic Pathology, University of the Ryukyus Hospital, Okinawa, Japan;
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KEI TANAKA
4Department of Urology, Graduate School of Medicine, University of the Ryukyus, Okinawa, Japan;
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KAZUHO MORICHIKA
5Division of Endocrinology, Diabetes and Metabolism, Hematology, Rheumatology, (Second Department of Internal Medicine), Graduate School of Medicine, University of the Ryukyus, Okinawa, Japan;
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FUMI KAWAKAMI
6Department of Pathology and Cell Biology, Graduate School of Medicine, University of the Ryukyus, Okinawa, Japan;
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MARIKO TOMITA
7Department of Pathology and Oncology, Graduate School of Medicine, University of the Ryukyus, Okinawa, Japan;
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NAOKI WADA
7Department of Pathology and Oncology, Graduate School of Medicine, University of the Ryukyus, Okinawa, Japan;
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AKIRA YOGI
8Department of Radiology, Graduate School of Medicine, University of the Ryukyus, Okinawa, Japan;
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HIROAKI MASUZAKI
5Division of Endocrinology, Diabetes and Metabolism, Hematology, Rheumatology, (Second Department of Internal Medicine), Graduate School of Medicine, University of the Ryukyus, Okinawa, Japan;
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TADASHI HAMASAKI
9Department of Neurosurgery, Graduate School of Medicine, University of the Ryukyus, Okinawa, Japan
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Article Information

vol. 40 no. 3 1824-1831
DOI 
https://doi.org/10.21873/invivo.14336
PMID 
42049442

Published By 
International Institute of Anticancer Research
Print ISSN 
0258-851X
Online ISSN 
1791-7549
History 
  • Received January 29, 2026
  • Revision received February 26, 2026
  • Accepted March 4, 2026
  • Published online April 28, 2026.

Copyright & License 
Copyright © 2026 The Author(s). Published by the International Institute of Anticancer Research. This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

Author Information

  1. TESSHO MARUYAMA1⇑,
  2. YOHEI HOKAMA2,
  3. KAZUTAKA KISHABA2,
  4. TOMOMI KUNINAKA2,
  5. SHIGETAKA KOBAYASHI2,
  6. HIDEKI NAGAMINE2,
  7. HIROFUMI MIYAHIRA3,
  8. KEI TANAKA4,
  9. KAZUHO MORICHIKA5,
  10. FUMI KAWAKAMI6,
  11. MARIKO TOMITA7,
  12. NAOKI WADA7,
  13. AKIRA YOGI8,
  14. HIROAKI MASUZAKI5 and
  15. TADASHI HAMASAKI9
  1. 1Comprehensive Health Professions Education Center, University of the Ryukyus Hospital, Okinawa, Japan;
  2. 2Department of Neurosurgery, University of the Ryukyus Hospital, Okinawa, Japan;
  3. 3Department of Diagnostic Pathology, University of the Ryukyus Hospital, Okinawa, Japan;
  4. 4Department of Urology, Graduate School of Medicine, University of the Ryukyus, Okinawa, Japan;
  5. 5Division of Endocrinology, Diabetes and Metabolism, Hematology, Rheumatology, (Second Department of Internal Medicine), Graduate School of Medicine, University of the Ryukyus, Okinawa, Japan;
  6. 6Department of Pathology and Cell Biology, Graduate School of Medicine, University of the Ryukyus, Okinawa, Japan;
  7. 7Department of Pathology and Oncology, Graduate School of Medicine, University of the Ryukyus, Okinawa, Japan;
  8. 8Department of Radiology, Graduate School of Medicine, University of the Ryukyus, Okinawa, Japan;
  9. 9Department of Neurosurgery, Graduate School of Medicine, University of the Ryukyus, Okinawa, Japan
  1. Tessho Maruyama, MD, DDS, PhD, Comprehensive Health Professions Education Center, University of the Ryukyus Hospital, Okinawa, Japan. 1076 Kiyuna, Ginowan, Okinawa 901-2725, Japan. Tel: +81 988941301, e-mail: h075324{at}cs.u-ryukyu.ac.jp; tesshou.730{at}gmail.com
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Management of a Complex Orbital Post-transplantation Lymphoproliferative Disorder: A Case Report and Literature Review
TESSHO MARUYAMA, YOHEI HOKAMA, KAZUTAKA KISHABA, TOMOMI KUNINAKA, SHIGETAKA KOBAYASHI, HIDEKI NAGAMINE, HIROFUMI MIYAHIRA, KEI TANAKA, KAZUHO MORICHIKA, FUMI KAWAKAMI, MARIKO TOMITA, NAOKI WADA, AKIRA YOGI, HIROAKI MASUZAKI, TADASHI HAMASAKI
In Vivo May 2026, 40 (3) 1824-1831; DOI: 10.21873/invivo.14336

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Management of a Complex Orbital Post-transplantation Lymphoproliferative Disorder: A Case Report and Literature Review
TESSHO MARUYAMA, YOHEI HOKAMA, KAZUTAKA KISHABA, TOMOMI KUNINAKA, SHIGETAKA KOBAYASHI, HIDEKI NAGAMINE, HIROFUMI MIYAHIRA, KEI TANAKA, KAZUHO MORICHIKA, FUMI KAWAKAMI, MARIKO TOMITA, NAOKI WADA, AKIRA YOGI, HIROAKI MASUZAKI, TADASHI HAMASAKI
In Vivo May 2026, 40 (3) 1824-1831; DOI: 10.21873/invivo.14336
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Keywords

  • Post-transplantation lymphoproliferative disorder
  • orbital lymphoma
  • reduction in immunosuppressant treatment
  • transcranial biopsy
  • kidney transplantation
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