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Research ArticleClinical Studies
Open Access

Comparison of Early Response to Selumetinib Therapy in Adolescents and Children With NF1-related Plexiform Neurofibromas

JAGODA STYCZYŃSKA, AGATA MARJAŃSKA, AGNIESZKA JATCZAK-GACA, MAREK KARWACKI, JUSTYNA WALENCIAK, KATARZYNA GARUS, KATARZYNA BILSKA, AGNIESZKA MIZIA-MALARZ, WANDA BADOWSKA, DOROTA SŁAWIŃSKA, JADWIGA WĘCŁAWEK-TOMPOL, RADOSŁAW CHABER, EWA BIEŃ, MICHALINA JEZIERSKA, GRAŻYNA KAROLCZYK, JOLANTA SKALSKA-SADOWSKA and JAN STYCZYŃSKI
In Vivo May 2026, 40 (3) 1621-1627; DOI: https://doi.org/10.21873/invivo.14312
JAGODA STYCZYŃSKA
1Department of Pediatric Hematology, Oncology, Immunology and Transplantology, Collegium Medicum, Nicolaus Copernicus University Torun, Jurasz University Hospital, Bydgoszcz, Poland;
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  • For correspondence: jagasadlok{at}gmail.com
AGATA MARJAŃSKA
1Department of Pediatric Hematology, Oncology, Immunology and Transplantology, Collegium Medicum, Nicolaus Copernicus University Torun, Jurasz University Hospital, Bydgoszcz, Poland;
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AGNIESZKA JATCZAK-GACA
1Department of Pediatric Hematology, Oncology, Immunology and Transplantology, Collegium Medicum, Nicolaus Copernicus University Torun, Jurasz University Hospital, Bydgoszcz, Poland;
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MAREK KARWACKI
2Department of Pediatric Hematology and Oncology, Clinical Transplantology and Pediatrics, Medical University of Warsaw, Warsaw, Poland;
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JUSTYNA WALENCIAK
3Department of Pediatrics, Oncology and Hematology, Medical University, Łódź, Poland;
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KATARZYNA GARUS
4Department of Pediatric Oncology and Hematology, Institute of Pediatrics, Jagiellonian University Medical College, Kraków, Poland;
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KATARZYNA BILSKA
5Department of Oncology and Surgical Oncology for Children and Youth, Institute of Mother and Child, Warsaw, Poland;
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AGNIESZKA MIZIA-MALARZ
6Department of Oncology, Hematology and Chemotherapy, Division of Pediatrics, Medical University of Silesia, Upper Silesian Child Health Centre, Katowice, Poland;
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WANDA BADOWSKA
7Department of Pediatrics and Hematology and Oncology, Province Children’s Hospital, Olsztyn, Poland;
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DOROTA SŁAWIŃSKA
8Department of Pediatric Haematology and Oncology and Transplantology, Medical University, Lublin, Poland;
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JADWIGA WĘCŁAWEK-TOMPOL
9Department of Pediatric Hematology/Oncology and BMT, Medical University, Wrocław, Poland;
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RADOSŁAW CHABER
10Department of Pediatrics, Institute of Medical Sciences, Collegium Medicum, University of Rzeszów, Rzeszów, Poland;
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EWA BIEŃ
11Department of Pediatrics, Hematology and Oncology, Medical University, Gdańsk, Poland;
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MICHALINA JEZIERSKA
11Department of Pediatrics, Hematology and Oncology, Medical University, Gdańsk, Poland;
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GRAŻYNA KAROLCZYK
12Department of Pediatric Oncology and Hematology, Children’s Hospital in Kielce, Kielce, Poland;
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JOLANTA SKALSKA-SADOWSKA
13Department of Pediatric Oncology, Hematology and Transplantology, Poznań University of Medical Sciences, Poznań, Poland
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JAN STYCZYŃSKI
1Department of Pediatric Hematology, Oncology, Immunology and Transplantology, Collegium Medicum, Nicolaus Copernicus University Torun, Jurasz University Hospital, Bydgoszcz, Poland;
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In Vivo: 40 (3)
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Vol. 40, Issue 3
May-June 2026
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Comparison of Early Response to Selumetinib Therapy in Adolescents and Children With NF1-related Plexiform Neurofibromas
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Comparison of Early Response to Selumetinib Therapy in Adolescents and Children With NF1-related Plexiform Neurofibromas
JAGODA STYCZYŃSKA, AGATA MARJAŃSKA, AGNIESZKA JATCZAK-GACA, MAREK KARWACKI, JUSTYNA WALENCIAK, KATARZYNA GARUS, KATARZYNA BILSKA, AGNIESZKA MIZIA-MALARZ, WANDA BADOWSKA, DOROTA SŁAWIŃSKA, JADWIGA WĘCŁAWEK-TOMPOL, RADOSŁAW CHABER, EWA BIEŃ, MICHALINA JEZIERSKA, GRAŻYNA KAROLCZYK, JOLANTA SKALSKA-SADOWSKA, JAN STYCZYŃSKI
In Vivo May 2026, 40 (3) 1621-1627; DOI: 10.21873/invivo.14312

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Comparison of Early Response to Selumetinib Therapy in Adolescents and Children With NF1-related Plexiform Neurofibromas
JAGODA STYCZYŃSKA, AGATA MARJAŃSKA, AGNIESZKA JATCZAK-GACA, MAREK KARWACKI, JUSTYNA WALENCIAK, KATARZYNA GARUS, KATARZYNA BILSKA, AGNIESZKA MIZIA-MALARZ, WANDA BADOWSKA, DOROTA SŁAWIŃSKA, JADWIGA WĘCŁAWEK-TOMPOL, RADOSŁAW CHABER, EWA BIEŃ, MICHALINA JEZIERSKA, GRAŻYNA KAROLCZYK, JOLANTA SKALSKA-SADOWSKA, JAN STYCZYŃSKI
In Vivo May 2026, 40 (3) 1621-1627; DOI: 10.21873/invivo.14312
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Keywords

  • Neurofibromatosis type 1
  • plexiform neurofibroma
  • selumetinib
  • adolescents
  • children
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