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Research ArticleExperimental Studies
Open Access

The Asn680Ser Variant Negatively Impacted the Ovarian Response to Controlled Ovarian Stimulation in Thai Female Infertility

NUTTANICHA BOONLONG, LINGLING SALANG, SIRIPORN PROUNGVITAYA, PORNSUDA MARAMING, JUREERUT DADUANG, THANIDA PONGSRITASANA, SINEENART SUKKASAME and SONGPOL HAOHAN
In Vivo May 2026, 40 (3) 1497-1508; DOI: https://doi.org/10.21873/invivo.14300
NUTTANICHA BOONLONG
1Graduate School, Khon Kaen University, Khon Kaen, Thailand;
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LINGLING SALANG
2Department of Obstetrics and Gynecology Srinagarind Hospital, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand;
3Center of Excellence for Infertility Treatment, Srinagarind Hospital, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand;
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SIRIPORN PROUNGVITAYA
4School of Medical Technology, Faculty of Associated Medical Sciences, Khon Kaen University, Khon Kaen, Thailand;
5Centre of Research and Development of Medical Diagnostic Laboratories, Faculty of Associated Medical Sciences, Khon Kaen University, Khon Kaen, Thailand
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PORNSUDA MARAMING
4School of Medical Technology, Faculty of Associated Medical Sciences, Khon Kaen University, Khon Kaen, Thailand;
5Centre of Research and Development of Medical Diagnostic Laboratories, Faculty of Associated Medical Sciences, Khon Kaen University, Khon Kaen, Thailand
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JUREERUT DADUANG
4School of Medical Technology, Faculty of Associated Medical Sciences, Khon Kaen University, Khon Kaen, Thailand;
5Centre of Research and Development of Medical Diagnostic Laboratories, Faculty of Associated Medical Sciences, Khon Kaen University, Khon Kaen, Thailand
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THANIDA PONGSRITASANA
2Department of Obstetrics and Gynecology Srinagarind Hospital, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand;
3Center of Excellence for Infertility Treatment, Srinagarind Hospital, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand;
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SINEENART SUKKASAME
2Department of Obstetrics and Gynecology Srinagarind Hospital, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand;
3Center of Excellence for Infertility Treatment, Srinagarind Hospital, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand;
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SONGPOL HAOHAN
4School of Medical Technology, Faculty of Associated Medical Sciences, Khon Kaen University, Khon Kaen, Thailand;
5Centre of Research and Development of Medical Diagnostic Laboratories, Faculty of Associated Medical Sciences, Khon Kaen University, Khon Kaen, Thailand
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  • For correspondence: songha{at}kku.ac.th
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Article Information

vol. 40 no. 3 1497-1508
DOI 
https://doi.org/10.21873/invivo.14300
PMID 
42049431

Published By 
International Institute of Anticancer Research
Print ISSN 
0258-851X
Online ISSN 
1791-7549
History 
  • Received January 10, 2026
  • Revision received February 9, 2026
  • Accepted February 13, 2026
  • Published online April 28, 2026.

Copyright & License 
Copyright © 2026 The Author(s). Published by the International Institute of Anticancer Research. This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

Author Information

  1. NUTTANICHA BOONLONG1,
  2. LINGLING SALANG2,3,
  3. SIRIPORN PROUNGVITAYA4,5,
  4. PORNSUDA MARAMING4,5,
  5. JUREERUT DADUANG4,5,
  6. THANIDA PONGSRITASANA2,3,
  7. SINEENART SUKKASAME2,3 and
  8. SONGPOL HAOHAN4,5⇑
  1. 1Graduate School, Khon Kaen University, Khon Kaen, Thailand;
  2. 2Department of Obstetrics and Gynecology Srinagarind Hospital, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand;
  3. 3Center of Excellence for Infertility Treatment, Srinagarind Hospital, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand;
  4. 4School of Medical Technology, Faculty of Associated Medical Sciences, Khon Kaen University, Khon Kaen, Thailand;
  5. 5Centre of Research and Development of Medical Diagnostic Laboratories, Faculty of Associated Medical Sciences, Khon Kaen University, Khon Kaen, Thailand
  1. Songpol Haohan, PhD, School of Medical Technology, Faculty of Associated Medical Sciences, Khon Kaen University, 123 Mittraphap Road, Muang Khon Kaen, Khon Kaen 40002, Thailand. Tel: +66 872291418, e-mail: songha{at}kku.ac.th
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The Asn680Ser Variant Negatively Impacted the Ovarian Response to Controlled Ovarian Stimulation in Thai Female Infertility
NUTTANICHA BOONLONG, LINGLING SALANG, SIRIPORN PROUNGVITAYA, PORNSUDA MARAMING, JUREERUT DADUANG, THANIDA PONGSRITASANA, SINEENART SUKKASAME, SONGPOL HAOHAN
In Vivo May 2026, 40 (3) 1497-1508; DOI: 10.21873/invivo.14300

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The Asn680Ser Variant Negatively Impacted the Ovarian Response to Controlled Ovarian Stimulation in Thai Female Infertility
NUTTANICHA BOONLONG, LINGLING SALANG, SIRIPORN PROUNGVITAYA, PORNSUDA MARAMING, JUREERUT DADUANG, THANIDA PONGSRITASANA, SINEENART SUKKASAME, SONGPOL HAOHAN
In Vivo May 2026, 40 (3) 1497-1508; DOI: 10.21873/invivo.14300
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Keywords

  • Asn680Ser
  • −29G>A
  • −211G>T
  • FSHR polymorphism
  • ovarian stimulation
  • poor response
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