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Research ArticleExperimental Studies
Open Access

Microarray Analysis of Human Abdominal Aortic Aneurysm With Emphasis on Cardiovascular Genes Revealed Differentially Expressed Genes

SONG LU, LI PING LI, JOHN V. WHITE, XIAOYING ZHANG, IFEYINWA NWANESHIUDU, ADAOBI NWANESHIUDU, NECTARIA NTAOULA, JOHN GAUGHAN, DIMITRI S. MONOS, WAN-LU LIN, CHARALAMBOS C. SOLOMIDES, EMILIA L. OLESZAK and CHRIS D. PLATSOUCAS
In Vivo May 2026, 40 (3) 1327-1347; DOI: https://doi.org/10.21873/invivo.14286
SONG LU
1Department of Microbiology and Immunology, Temple University School of Medicine, Philadelphia, PA, U.S.A.;
2Mon Health Medical Center, Department of Pathology, Morgantown, WV, U.S.A.;
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LI PING LI
1Department of Microbiology and Immunology, Temple University School of Medicine, Philadelphia, PA, U.S.A.;
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JOHN V. WHITE
3Department of Surgery, Advocate Lutheran General Hospital and University of Illinois School of Medicine, Park Ridge, IL, U.S.A.;
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XIAOYING ZHANG
1Department of Microbiology and Immunology, Temple University School of Medicine, Philadelphia, PA, U.S.A.;
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IFEYINWA NWANESHIUDU
1Department of Microbiology and Immunology, Temple University School of Medicine, Philadelphia, PA, U.S.A.;
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ADAOBI NWANESHIUDU
1Department of Microbiology and Immunology, Temple University School of Medicine, Philadelphia, PA, U.S.A.;
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NECTARIA NTAOULA
1Department of Microbiology and Immunology, Temple University School of Medicine, Philadelphia, PA, U.S.A.;
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JOHN GAUGHAN
4Department of Medicine, Cooper University Hospital, School of Medicine of Rowan University, Camden, NJ, U.S.A.;
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DIMITRI S. MONOS
5Department of Pathology and Laboratory Medicine, University of Pennsylvania, Perelman School of Medicine, Philadelphia, PA, U.S.A.;
6The Children’s Hospital of Philadelphia, Philadelphia, PA, U.S.A.;
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WAN-LU LIN
1Department of Microbiology and Immunology, Temple University School of Medicine, Philadelphia, PA, U.S.A.;
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CHARALAMBOS C. SOLOMIDES
7Department of Pathology and Genomic Medicine, Thomas Jefferson University Hospital, Philadelphia, PA, U.S.A.;
8Department of Pathology and Laboratory Medicine, Temple University School of Medicine, Philadelphia, PA, U.S.A.;
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EMILIA L. OLESZAK
9Department of Anatomy and Cell Biology, Temple University School of Medicine, Philadelphia, PA, U.S.A.;
10Department of Biological Sciences, Old Dominion University, Norfolk, VA, U.S.A;
11Center for Molecular Medicine, Old Dominion University, Norfolk, VA, U.S.A.
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CHRIS D. PLATSOUCAS
1Department of Microbiology and Immunology, Temple University School of Medicine, Philadelphia, PA, U.S.A.;
10Department of Biological Sciences, Old Dominion University, Norfolk, VA, U.S.A;
11Center for Molecular Medicine, Old Dominion University, Norfolk, VA, U.S.A.
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  • For correspondence: cplatsoucas{at}odu.edu
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Article Information

vol. 40 no. 3 1327-1347
DOI 
https://doi.org/10.21873/invivo.14286
PMID 
42049434

Published By 
International Institute of Anticancer Research
Print ISSN 
0258-851X
Online ISSN 
1791-7549
History 
  • Received July 12, 2025
  • Revision received January 16, 2026
  • Accepted February 6, 2026
  • Published online April 28, 2026.

Copyright & License 
Copyright © 2026 The Author(s). Published by the International Institute of Anticancer Research. This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

Author Information

  1. SONG LU1,2,
  2. LI PING LI1,
  3. JOHN V. WHITE3,
  4. XIAOYING ZHANG1,
  5. IFEYINWA NWANESHIUDU1,
  6. ADAOBI NWANESHIUDU1,
  7. NECTARIA NTAOULA1,
  8. JOHN GAUGHAN4,
  9. DIMITRI S. MONOS5,6,
  10. WAN-LU LIN1,
  11. CHARALAMBOS C. SOLOMIDES7,8,
  12. EMILIA L. OLESZAK9,10,11 and
  13. CHRIS D. PLATSOUCAS1,10,11⇑
  1. 1Department of Microbiology and Immunology, Temple University School of Medicine, Philadelphia, PA, U.S.A.;
  2. 2Mon Health Medical Center, Department of Pathology, Morgantown, WV, U.S.A.;
  3. 3Department of Surgery, Advocate Lutheran General Hospital and University of Illinois School of Medicine, Park Ridge, IL, U.S.A.;
  4. 4Department of Medicine, Cooper University Hospital, School of Medicine of Rowan University, Camden, NJ, U.S.A.;
  5. 5Department of Pathology and Laboratory Medicine, University of Pennsylvania, Perelman School of Medicine, Philadelphia, PA, U.S.A.;
  6. 6The Children’s Hospital of Philadelphia, Philadelphia, PA, U.S.A.;
  7. 7Department of Pathology and Genomic Medicine, Thomas Jefferson University Hospital, Philadelphia, PA, U.S.A.;
  8. 8Department of Pathology and Laboratory Medicine, Temple University School of Medicine, Philadelphia, PA, U.S.A.;
  9. 9Department of Anatomy and Cell Biology, Temple University School of Medicine, Philadelphia, PA, U.S.A.;
  10. 10Department of Biological Sciences, Old Dominion University, Norfolk, VA, U.S.A;
  11. 11Center for Molecular Medicine, Old Dominion University, Norfolk, VA, U.S.A.
  1. Chris D. Platsoucas, PhD, D.Sc. (h.c.), MGB, Room 254, Department of Biological Sciences, Old Dominion University, Norfolk, VA 23529, USA. Mobile: +1 2153008610, e-mail: cplatsoucas{at}odu.edu
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Microarray Analysis of Human Abdominal Aortic Aneurysm With Emphasis on Cardiovascular Genes Revealed Differentially Expressed Genes
SONG LU, LI PING LI, JOHN V. WHITE, XIAOYING ZHANG, IFEYINWA NWANESHIUDU, ADAOBI NWANESHIUDU, NECTARIA NTAOULA, JOHN GAUGHAN, DIMITRI S. MONOS, WAN-LU LIN, CHARALAMBOS C. SOLOMIDES, EMILIA L. OLESZAK, CHRIS D. PLATSOUCAS
In Vivo May 2026, 40 (3) 1327-1347; DOI: 10.21873/invivo.14286

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Microarray Analysis of Human Abdominal Aortic Aneurysm With Emphasis on Cardiovascular Genes Revealed Differentially Expressed Genes
SONG LU, LI PING LI, JOHN V. WHITE, XIAOYING ZHANG, IFEYINWA NWANESHIUDU, ADAOBI NWANESHIUDU, NECTARIA NTAOULA, JOHN GAUGHAN, DIMITRI S. MONOS, WAN-LU LIN, CHARALAMBOS C. SOLOMIDES, EMILIA L. OLESZAK, CHRIS D. PLATSOUCAS
In Vivo May 2026, 40 (3) 1327-1347; DOI: 10.21873/invivo.14286
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Keywords

  • Abdominal aortic aneurysm
  • microarray
  • qRT-PCR
  • gene expression
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