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Review ArticleReview
Open Access

Slow-release L-cysteine Lozenges in Smoking Cessation: Meta-analysis of Two Randomized Controlled Trials

Kari Syrjänen and Osmo Suovaniemi
In Vivo January 2026, 40 (1) 39-49; DOI: https://doi.org/10.21873/invivo.14171
Kari Syrjänen
1Department of Clinical Research, Biohit Oyj, Helsinki, Finland;
2SMW Consultants Ltd, Kaarina, Finland
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  • For correspondence: kasyrja{at}saunalahti.fi
Osmo Suovaniemi
1Department of Clinical Research, Biohit Oyj, Helsinki, Finland;
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    Figure 1.

    Forest plot for the summary effect estimates* of Acetium® intervention in the intention-to-treat (ITT) group. *PPA, Point prevalence of abstinence.

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    Figure 2.

    Forest plot for the summary effect estimates* of Acetium® intervention in the per protocol (PP) group. *PPA, Point prevalence of abstinence.

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    Figure 3.

    Study heterogeneity evaluated by Galbraith plot in the intention-to-treat (ITT) compliance group.

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    Figure 4.

    Study heterogeneity evaluated by Galbraith plot in the per protocol (PP) compliance group.

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    Figure 5.

    Funnel plot for the eventual publication bias in the intention-to-treat (ITT) analysis.

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    Figure 6.

    Funnel plot for the eventual publication in the per protocol (PP) analysis.

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In Vivo: 40 (1)
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Vol. 40, Issue 1
January-February 2026
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Slow-release L-cysteine Lozenges in Smoking Cessation: Meta-analysis of Two Randomized Controlled Trials
Kari Syrjänen, Osmo Suovaniemi
In Vivo Jan 2026, 40 (1) 39-49; DOI: 10.21873/invivo.14171

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Slow-release L-cysteine Lozenges in Smoking Cessation: Meta-analysis of Two Randomized Controlled Trials
Kari Syrjänen, Osmo Suovaniemi
In Vivo Jan 2026, 40 (1) 39-49; DOI: 10.21873/invivo.14171
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Keywords

  • Smoking intervention
  • slow-release L-cysteine
  • lozenge
  • randomized controlled trial
  • meta-analysis
  • review
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