Contribution of Interleukin-4 Promoter Genotypes to Gastric Cancer Risk in Taiwan

CHUN-KAI FU; HSU-TUNG LEE; YA-CHEN YANG; JAW-CHYUN CHEN; MEI-DUE YANG; YUN-CHI WANG; HOU-YU SHIH; CHIA-WEN TSAI; DA-TIAN BAU; WEN-SHIN CHANG

doi:10.21873/invivo.13990

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Contribution of Interleukin-4 Promoter Genotypes to Gastric Cancer Risk in Taiwan

CHUN-KAI FU, HSU-TUNG LEE, YA-CHEN YANG, JAW-CHYUN CHEN, MEI-DUE YANG, YUN-CHI WANG, HOU-YU SHIH, CHIA-WEN TSAI, DA-TIAN BAU and WEN-SHIN CHANG

In Vivo July 2025, 39 (4) 1912-1923; DOI: https://doi.org/10.21873/invivo.13990

CHUN-KAI FU

1Graduate Institute of Biomedical Sciences, China Medical University, Taichung, Taiwan, R.O.C.;

2Taichung Armed Forces General Hospital, Taichung, Taiwan, R.O.C.;

3National Defense Medical Center, Taipei, Taiwan, R.O.C.;

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HSU-TUNG LEE

4Department of Post-Baccalaureate Medicine, College of Medicine, National Chung Hsing University, Taichung, Taiwan, R.O.C.;

5Division of Neurosurgical Oncology, Department of Neurological Institute, Taichung Veterans General Hospital, Taichung, Taiwan, R.O.C.;

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YA-CHEN YANG

6Department of Food Nutrition and Health Biotechnology, Asia University, Taichung, Taiwan, R.O.C.;

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JAW-CHYUN CHEN

7Department of Medicinal Botanicals and Foods on Health Applications, Da-Yeh University, Changhua, Taiwan, R.O.C.;

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MEI-DUE YANG

8Terry Fox Cancer Research Laboratory, Department of Medical Research, China Medical University Hospital, Taichung, Taiwan, R.O.C.;

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YUN-CHI WANG

1Graduate Institute of Biomedical Sciences, China Medical University, Taichung, Taiwan, R.O.C.;

8Terry Fox Cancer Research Laboratory, Department of Medical Research, China Medical University Hospital, Taichung, Taiwan, R.O.C.;

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HOU-YU SHIH

1Graduate Institute of Biomedical Sciences, China Medical University, Taichung, Taiwan, R.O.C.;

8Terry Fox Cancer Research Laboratory, Department of Medical Research, China Medical University Hospital, Taichung, Taiwan, R.O.C.;

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CHIA-WEN TSAI

1Graduate Institute of Biomedical Sciences, China Medical University, Taichung, Taiwan, R.O.C.;

8Terry Fox Cancer Research Laboratory, Department of Medical Research, China Medical University Hospital, Taichung, Taiwan, R.O.C.;

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DA-TIAN BAU

1Graduate Institute of Biomedical Sciences, China Medical University, Taichung, Taiwan, R.O.C.;

8Terry Fox Cancer Research Laboratory, Department of Medical Research, China Medical University Hospital, Taichung, Taiwan, R.O.C.;

9Department of Bioinformatics and Medical Engineering, Asia University, Taichung, Taiwan, R.O.C.

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For correspondence: 013280{at}tool.caaumed.org.tw

WEN-SHIN CHANG

1Graduate Institute of Biomedical Sciences, China Medical University, Taichung, Taiwan, R.O.C.;

8Terry Fox Cancer Research Laboratory, Department of Medical Research, China Medical University Hospital, Taichung, Taiwan, R.O.C.;

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For correspondence: 031002{at}tool.caaumed.org.tw

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Figure 1.
Physical map of IL-4 T-1099G (rs2243248), C-589T (rs2243250), and C-33T (rs2070874) polymorphic sites.

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Contribution of Interleukin-4 Promoter Genotypes to Gastric Cancer Risk in Taiwan

CHUN-KAI FU, HSU-TUNG LEE, YA-CHEN YANG, JAW-CHYUN CHEN, MEI-DUE YANG, YUN-CHI WANG, HOU-YU SHIH, CHIA-WEN TSAI, DA-TIAN BAU, WEN-SHIN CHANG

In Vivo Jul 2025, 39 (4) 1912-1923; DOI: 10.21873/invivo.13990

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Contribution of Interleukin-4 Promoter Genotypes to Gastric Cancer Risk in Taiwan

CHUN-KAI FU, HSU-TUNG LEE, YA-CHEN YANG, JAW-CHYUN CHEN, MEI-DUE YANG, YUN-CHI WANG, HOU-YU SHIH, CHIA-WEN TSAI, DA-TIAN BAU, WEN-SHIN CHANG

In Vivo Jul 2025, 39 (4) 1912-1923; DOI: 10.21873/invivo.13990

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Keywords

Cancer risk
Gastric cancer
genotype
interleukin-4
single nucleotide polymorphism
Taiwan

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