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Research ArticleClinical Studies
Open Access

Steroid Premedication Impact on Efficacy and Cutaneous Toxicity of Enfortumab Vedotin for Advanced Urothelial Carcinoma

NOBUKI FURUBAYASHI, MANABU MOCHIDA, ATSUHIRO KIJIMA, YUSHI FUJIMOTO, MOTONOBU NAKAMURA and TAKAHITO NEGISHI
In Vivo May 2025, 39 (3) 1607-1614; DOI: https://doi.org/10.21873/invivo.13961
NOBUKI FURUBAYASHI
Department of Urology, NHO Kyushu Cancer Center, Fukuoka, Japan
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  • For correspondence: furubayashi.nobuki.yc{at}mail.hosp.go.jp
MANABU MOCHIDA
Department of Urology, NHO Kyushu Cancer Center, Fukuoka, Japan
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ATSUHIRO KIJIMA
Department of Urology, NHO Kyushu Cancer Center, Fukuoka, Japan
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YUSHI FUJIMOTO
Department of Urology, NHO Kyushu Cancer Center, Fukuoka, Japan
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MOTONOBU NAKAMURA
Department of Urology, NHO Kyushu Cancer Center, Fukuoka, Japan
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TAKAHITO NEGISHI
Department of Urology, NHO Kyushu Cancer Center, Fukuoka, Japan
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  • Figure 1.
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    Figure 1.

    Objective response rates with and without steroid premedication in patients treated with enfortumab vedotin.

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    Figure 2.

    Disease control rates with and without steroid premedication in patients treated with enfortumab vedotin.

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    Figure 3.

    Progression-free survival rates with and without steroid premedication in patients treated with enfortumab vedotin.

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    Figure 4.

    Incidence of enfortumab vedotin-related cutaneous toxicity (all grade) according to steroid premedication (with and without).

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    Figure 5.

    Incidence of enfortumab vedotin-related cutaneous toxicity (grade ≥3) according to steroid premedication (with and without).

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In Vivo: 39 (3)
In Vivo
Vol. 39, Issue 3
May-June 2025
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Steroid Premedication Impact on Efficacy and Cutaneous Toxicity of Enfortumab Vedotin for Advanced Urothelial Carcinoma
NOBUKI FURUBAYASHI, MANABU MOCHIDA, ATSUHIRO KIJIMA, YUSHI FUJIMOTO, MOTONOBU NAKAMURA, TAKAHITO NEGISHI
In Vivo May 2025, 39 (3) 1607-1614; DOI: 10.21873/invivo.13961

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Steroid Premedication Impact on Efficacy and Cutaneous Toxicity of Enfortumab Vedotin for Advanced Urothelial Carcinoma
NOBUKI FURUBAYASHI, MANABU MOCHIDA, ATSUHIRO KIJIMA, YUSHI FUJIMOTO, MOTONOBU NAKAMURA, TAKAHITO NEGISHI
In Vivo May 2025, 39 (3) 1607-1614; DOI: 10.21873/invivo.13961
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Keywords

  • urothelial carcinoma
  • enfortumab vedotin
  • cutaneous toxicity
  • steroid premedication
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