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Research ArticleClinical Studies
Open Access

Phase II Trial of Capecitabine Plus Bevacizumab for Elderly Patients With Metastatic Colorectal Cancer: OGSG 1102

TOSHIFUMI YAMAGUCHI, MOTOKI YOSHIDA, KOICHI TAIRA, SHINYA TOKUNAGA, TAKESHI KATO, MASATO NAKAMURA, NAOTOSHI SUGIMOTO, SOICHI FUMITA, MASAYOSHI YASUI, YASUHIRO MIYAKE, HISATO KAWAKAMI, YUKINORI KUROKAWA, TOSHIO SHIMOKAWA and TAROH SATOH
In Vivo May 2025, 39 (3) 1505-1513; DOI: https://doi.org/10.21873/invivo.13950
TOSHIFUMI YAMAGUCHI
1Cancer Chemotherapy Center, Osaka Medical and Pharmaceutical University, Osaka, Japan;
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  • For correspondence: toshifumi.yamaguchi{at}ompu.ac.jp
MOTOKI YOSHIDA
1Cancer Chemotherapy Center, Osaka Medical and Pharmaceutical University, Osaka, Japan;
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KOICHI TAIRA
2Department of Medical Oncology, Osaka City General Hospital, Osaka, Japan;
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SHINYA TOKUNAGA
2Department of Medical Oncology, Osaka City General Hospital, Osaka, Japan;
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TAKESHI KATO
3Department of Surgery, Kansai Rosai Hospital, Amagasaki, Japan;
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MASATO NAKAMURA
4Aizawa Comprehensive Cancer Center, Aizawa Hospital, Matsumoto, Japan;
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NAOTOSHI SUGIMOTO
5Department of Medical Oncology, Osaka International Cancer Institute, Osaka, Japan;
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SOICHI FUMITA
6Department of Medical Oncology, Kishiwada City Hospital, Kishiwada, Japan;
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MASAYOSHI YASUI
7Department of Surgery, Kaizuka City Hospital, Kaizuka, Japan;
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YASUHIRO MIYAKE
8Department of Surgery, Nishinomiya Municipal Central Hospital, Nishinomiya, Japan;
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HISATO KAWAKAMI
9Department of Medical Oncology, Kindai University Faculty of Medicine, Higashi-osaka, Japan;
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YUKINORI KUROKAWA
10Department of Gastroenterological Surgery, Osaka University Graduate School of Medicine, Osaka, Japan;
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TOSHIO SHIMOKAWA
11Department of Medical Data Science, Graduate School of Medicine, Wakayama Medical University, Wakayama, Japan
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TAROH SATOH
10Department of Gastroenterological Surgery, Osaka University Graduate School of Medicine, Osaka, Japan;
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    Figure 1.

    Kaplan-Meier curve of progression-free survival (PFS) in elderly patients with colorectal cancer treated with first-line capecitabine plus bevacizumab (N=33). CI: Confidence interval.

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    Figure 2.

    Kaplan-Meier curve of overall survival (OS) in elderly patients with colorectal cancer treated with first-line capecitabine plus bevacizumab (N=33). CI: Confidence interval.

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In Vivo: 39 (3)
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May-June 2025
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Phase II Trial of Capecitabine Plus Bevacizumab for Elderly Patients With Metastatic Colorectal Cancer: OGSG 1102
TOSHIFUMI YAMAGUCHI, MOTOKI YOSHIDA, KOICHI TAIRA, SHINYA TOKUNAGA, TAKESHI KATO, MASATO NAKAMURA, NAOTOSHI SUGIMOTO, SOICHI FUMITA, MASAYOSHI YASUI, YASUHIRO MIYAKE, HISATO KAWAKAMI, YUKINORI KUROKAWA, TOSHIO SHIMOKAWA, TAROH SATOH
In Vivo May 2025, 39 (3) 1505-1513; DOI: 10.21873/invivo.13950

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Phase II Trial of Capecitabine Plus Bevacizumab for Elderly Patients With Metastatic Colorectal Cancer: OGSG 1102
TOSHIFUMI YAMAGUCHI, MOTOKI YOSHIDA, KOICHI TAIRA, SHINYA TOKUNAGA, TAKESHI KATO, MASATO NAKAMURA, NAOTOSHI SUGIMOTO, SOICHI FUMITA, MASAYOSHI YASUI, YASUHIRO MIYAKE, HISATO KAWAKAMI, YUKINORI KUROKAWA, TOSHIO SHIMOKAWA, TAROH SATOH
In Vivo May 2025, 39 (3) 1505-1513; DOI: 10.21873/invivo.13950
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Keywords

  • colorectal cancer
  • elderly
  • capecitabine plus bevacizumab
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